SCHEMBL687302

SCHEMBL687302

O=C(O)c1cccc(N=C=S)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MIF P14174 1/20 0.52
MAPT P10636 4/20 0.50
RAB9A P51151 4/20 0.50
NPC1 O15118 3/20 0.50
SMN1; SMN2 Q16637 3/20 0.50
KMT2A Q03164 2/20 0.49
ALDH1A1 P00352 2/20 0.49
POLB P06746 2/20 0.49
L3MBTL1 Q9Y468 2/20 0.49
MEN1 O00255 1/20 0.49
GAA P10253 1/20 0.49
THRB P10828 1/20 0.49
PLCG1 P19174 1/20 0.49
LMNA P02545 1/20 0.48
CA12 O43570 1/20 0.47
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
CA6 P23280 1/20 0.47
CA9 Q16790 1/20 0.47
GLA P06280 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13123474 0.86 ATM (0.57) MIFMAPTRAB9ANPC1SMN1; SMN2
SCHEMBL2831122 0.84 ALDH1A1 (0.46) MIFMAPTRAB9ANPC1SMN1; SMN2
SCHEMBL31295541 0.84 PARP1 (0.48) MIFMAPTKMT2AALDH1A1POLB
SCHEMBL6121904 0.84 PARP1 (0.48) MIFMAPTKMT2AALDH1A1POLB
SCHEMBL4393821 0.83 MAPT (0.54) MAPTRAB9ANPC1SMN1; SMN2KMT2A
SCHEMBL69865 0.82 RAB9A (0.65) MAPTRAB9ANPC1SMN1; SMN2KMT2A
SCHEMBL31045928 0.82 RAB9A (0.65) MAPTRAB9ANPC1SMN1; SMN2KMT2A
SCHEMBL69866 0.82 RAB9A (0.65) MAPTRAB9ANPC1SMN1; SMN2KMT2A
Hydrochloric Acid SCHEMBL10393362 0.81 MAPT (0.53) MAPTRAB9ANPC1SMN1; SMN2KMT2A
Methane SCHEMBL7696978 0.81 MAPT (0.53) MAPTRAB9ANPC1SMN1; SMN2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 127 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117843276-B Multi-component composite steel slag grinding-aid excitant and preparation method thereof 华新水泥股份有限公司 2024-11-26 CN claimed
CN-118873488-A Coacervate and method for the production and use thereof 海诺生物科技有限公司 2024-11-01 CN claimed
CN-117843276-A Multi-component composite steel slag grinding-aid excitant and preparation method thereof 华新水泥股份有限公司 2024-04-09 CN claimed
CN-117342991-A Sustained-release high-alkaline cement reinforcing agent and preparation method and application thereof 华新水泥股份有限公司 2024-01-05 CN claimed
CN-113993997-A Modified cleaving enzymes, uses thereof and related kits ENCODIA 公司 2022-01-28 CN claimed
EP-0471345-B1 Determination of biogenous amines BOEHRINGER MANNHEIM GMBH (DE) 1995-08-02 EP claimed
EP-0471345-A1 Determination of biogenous amines Roche Diagnostics GmbH (DE) 1992-02-19 EP claimed
EP-0440329-A1 S-substituted carbonyl substituted betathioacrylamide biocides and fungicides ROHM AND HAAS COMPANY (US) 1991-08-07 EP claimed
CN-117843276-B Multi-component composite steel slag grinding-aid excitant and preparation method thereof 华新水泥股份有限公司 2024-11-26 CN disclosed
CN-118873488-A Coacervate and method for the production and use thereof 海诺生物科技有限公司 2024-11-01 CN disclosed
CN-117843276-A Multi-component composite steel slag grinding-aid excitant and preparation method thereof 华新水泥股份有限公司 2024-04-09 CN disclosed
CN-117342991-A Sustained-release high-alkaline cement reinforcing agent and preparation method and application thereof 华新水泥股份有限公司 2024-01-05 CN disclosed
CN-116685725-A Sequential encoding methods and related kits ENCODIA 公司 2023-09-01 CN disclosed
CN-114072499-A Method for preparing an analyte and related kit ENCODIA 公司 2022-02-18 CN disclosed
WO-1992011850-A2 USE OF CALPAIN INHIBITORS IN THE INHIBITION AND TREATMENT OF NEURODEGENERATION CORTEX PHARMACEUTICALS, INC. (US) 1992-07-23 WO disclosed
EP-0349243-B1 ANTIVIRAL COMBINATIONS AND COMPOUNDS THEREFOR THE WELLCOME FOUNDATION LIMITED (GB) 1992-04-01 EP disclosed
EP-0471345-A1 Determination of biogenous amines Roche Diagnostics GmbH (DE) 1992-02-19 EP disclosed
US-5089634-A Protease inhibitors, antiinflammatory agents, anticoagulants GEORGIA TECH RESEARCH CORPORATION (US) 1992-02-18 US disclosed
EP-0440329-A1 S-substituted carbonyl substituted betathioacrylamide biocides and fungicides ROHM AND HAAS COMPANY (US) 1991-08-07 EP disclosed
EP-0349243-A2 Antiviral combinations and compounds therefor THE WELLCOME FOUNDATION LIMITED (GB) 1990-01-03 EP disclosed