Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 8/20 | 0.64 |
| ▸ | ITGAV | P06756 | 4/20 | 0.64 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.64 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.64 |
| ▸ | ITGB5 | P18084 | 3/20 | 0.55 |
| ▸ | MC4R | P32245 | 10/20 | 0.50 |
| ▸ | MC5R | P33032 | 10/20 | 0.50 |
| ▸ | MC3R | P41968 | 10/20 | 0.50 |
| ▸ | MC1R | Q01726 | 10/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.50 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL279121 | 1.00 | ITGB3 (0.64) | ITGB3ITGAVITGB1ITGA5ITGB5 | |
| SCHEMBL16177741 | 0.93 | ITGB3 (0.61) | ITGB3ITGAVITGB1ITGA5ITGB5 | |
| SCHEMBL14885782 | 0.93 | ITGB3 (0.61) | ITGB3ITGAVITGB1ITGA5ITGB5 | |
| SCHEMBL14075719 | 0.90 | ITGB3 (0.54) | ITGB3ITGAVITGB1ITGA5ITGB5 | |
| SCHEMBL16995729 | 0.88 | ITGB3 (0.58) | ITGB3ITGAVITGB1ITGA5ITGB5 | |
| SCHEMBL14585830 | 0.88 | ITGB3 (0.53) | ITGB3ITGAVITGB1ITGA5ITGB5 | |
| SCHEMBL24285406 | 0.88 | ITGB3 (0.60) | ITGB3ITGAVITGB1ITGA5ITGB5 | |
| SCHEMBL10138534 | 0.88 | ITGB3 (0.60) | ITGB3ITGAVITGB1ITGA5ITGB5 | |
| SCHEMBL15397366 | 0.88 | ITGB3 (0.60) | ITGB3ITGAVITGB1ITGA5ITGB5 | |
| SCHEMBL18968795 | 0.88 | ITGB3 (0.55) | ITGB3ITGAVITGB1ITGA5ITGB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6537520-B1 | Diagnosis and treatment of cancer; kit containing compound having peptide or peptidomimetic functionality that binds to a alpha v beta 3 receptor linked to a chelator | BRISTOL-MYERS SQUIBB PHARMA COMPANY | 2003-03-25 | — | — | US | disclosed |