Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 3/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4685972 | 0.93 | HTT (0.43) | HTTALDH1A1L3MBTL1NAMPTCA9 | |
| SCHEMBL4685969 | 0.93 | HTT (0.43) | HTTALDH1A1L3MBTL1NAMPTCA9 | |
| SCHEMBL6641525 | 0.84 | CYP2C9 (0.41) | ALDH1A1RAB9ATPSAB1KLKB1MAPT | |
| SCHEMBL13325143 | 0.79 | IDO1 (0.53) | ALDH1A1CA9RAB9AGAALMNA | |
| SCHEMBL19494294 | 0.79 | IDO1 (0.53) | ALDH1A1CA9RAB9AGAALMNA | |
| SCHEMBL4678197 | 0.77 | HTT (0.58) | HTTALDH1A1GAALMNASMN1; SMN2 | |
| SCHEMBL4678201 | 0.77 | HTT (0.58) | HTTALDH1A1GAALMNASMN1; SMN2 | |
| SCHEMBL4679515 | 0.76 | MEN1 (0.45) | ALDH1A1RAB9AGAAMAPT | |
| SCHEMBL4679517 | 0.76 | MEN1 (0.45) | ALDH1A1RAB9AGAAMAPT | |
| SCHEMBL8566519 | 0.75 | IDO1 (0.36) | LOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1198456-A2 | POTASSIUM CHANNEL OPENERS | Abbott Laboratories (US) | 2002-04-24 | — | — | EP | disclosed |
| WO-2001009096-A2 | POTASSIUM CHANNEL OPENERS | ABBOTT LABORATORIES (US) | 2001-02-08 | — | — | WO | disclosed |