⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2225856 | 0.72 | — | — | |
| SCHEMBL7586060 | 0.67 | — | — | |
| SCHEMBL27770285 | 0.67 | — | — | |
| SCHEMBL56391 | 0.64 | — | — | |
| SCHEMBL16037462 | 0.64 | ALDH1A1 (1.00) | — | |
| SCHEMBL18460285 | 0.64 | — | — | |
| SCHEMBL2683512 | 0.60 | — | — | |
| SCHEMBL30321467 | 0.60 | — | — | |
| Lithium SCHEMBL29763173 | 0.60 | — | — | |
| Lithium SCHEMBL29833770 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113423842-A | Probes having octamine or octamine derivatives bound thereto and uses thereof | 柏业公司 | 2021-09-21 | — | — | CN | disclosed |
| US-RE45907-E1 | Functionalized stilbene derivatives as improved vascular targeting agents | OXIGENE, INC. (US) | 2016-03-01 | — | — | US | disclosed |
| US-RE45720-E1 | Functionalized stilbene derivatives as improved vascular targeting agents | OXIGENE, INC. (US) | 2015-10-06 | — | — | US | disclosed |
| US-7384925-B2 | 2' Hydroxy-3'-bromo-3,4,4',5-tetramethoxy-(Z)-stilbene; antimitotic agent; inhibits the assembly of tubulin into microtubules; anticarcinogenic: solid tumor cancers, neovascularization; tubulin-binding stilbenoid analogs structurally related to combretastatin A-1 and A-4 (extract from willow tree) | OXIGENE, INC. (US) | 2008-06-10 | — | — | US | disclosed |
| CN-1501961-A | Thermoplastic elastomer composition and molded object thereof | ס�ѻ�ѧ��ҵ��ʽ���� | 2004-06-02 | — | — | CN | disclosed |
| EP-0979233-A4 | METHOD FOR SOLUTION PHASE SYNTHESIS OF OLIGONUCLEOTIDES | PROLIGO L L C (US) | 2001-03-21 | — | — | EP | disclosed |
| EP-0979233-A1 | METHOD FOR SOLUTION PHASE SYNTHESIS OF OLIGONUCLEOTIDES | NeXstar Pharmaceuticals, Inc. (US) | 2000-02-16 | — | — | EP | disclosed |
| WO-1998047910-A1 | METHOD FOR SOLUTION PHASE SYNTHESIS OF OLIGONUCLEOTIDES | PROLIGO LLC (US) | 1998-10-29 | — | — | WO | disclosed |