SCHEMBL7744606

SCHEMBL7744606

C=CC(=O)NCC(C)C.[NaH]

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.52
ALDH1A1 P00352 1/20 0.52
MAPK1 P28482 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
CYP2D6 P10635 1/20 0.50
CYP2C19 P33261 1/20 0.50
CNR2 P34972 5/20 0.44
CNR1 P21554 3/20 0.44
PPARG P37231 2/20 0.44
PPARD Q03181 2/20 0.44
PPARA Q07869 2/20 0.44
ZDHHC20 Q5W0Z9 1/20 0.44
ZDHHC2 Q9UIJ5 1/20 0.44
MMP1 P03956 1/20 0.43
MMP8 P22894 1/20 0.43
HPGD P15428 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
CETP P11597 1/20 0.38
GAA P10253 1/20 0.37
KMT2A Q03164 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL372689 0.98
SCHEMBL29770830 0.95 TSHR (0.52) TSHRALDH1A1MAPK1TDP1CYP2D6
Acrylic Acid SCHEMBL20528130 0.94 CYP2D6 (0.50) TSHRALDH1A1MAPK1TDP1CYP2D6
Acrylamide SCHEMBL15635047 0.92 TSHR (0.45) TSHRALDH1A1MAPK1TDP1CYP2D6
Formic Acid SCHEMBL28269716 0.91 TSHR (0.48) TSHRALDH1A1MAPK1TDP1CYP2D6
Phosphonic Acid SCHEMBL28266598 0.90 TSHR (0.46) TSHRALDH1A1MAPK1TDP1CYP2D6
Acrylamide SCHEMBL6553344 0.90 TSHR (0.46) TSHRALDH1A1MAPK1TDP1CYP2D6
Sulfuric Acid SCHEMBL182294 0.90 CYP2D6 (0.50) TSHRALDH1A1MAPK1TDP1CYP2D6
Methacrylic Acid SCHEMBL4620872 0.86 TSHR (0.48) TSHRALDH1A1MAPK1TDP1CYP2D6
SCHEMBL18755013 0.84 TSHR (0.54) TSHRALDH1A1MAPK1TDP1CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4601603-A1 COMPOSITION COMPRISING A NON-IONIC SURFACTANT, A HYDROCARBON-BASED OIL, A BUTTER AND A WAX L'OREAL (FR) 2025-08-20 EP disclosed
WO-2024079308-A1 COMPOSITION COMPRISING A NON-IONIC SURFACTANT, A HYDROCARBON-BASED OIL, A BUTTER AND A WAX L'OREAL (FR) 2024-04-18 WO disclosed
WO-2023052594-A1 O/W EMULSION WITH C-GLYCOSIDE AND SPECIFIC SURFACTANTS L'OREAL (FR) 2023-04-06 WO disclosed
CN-114845688-A Retinol-based essence 欧莱雅 2022-08-02 CN disclosed
EP-3897548-A1 COMPOSITION COMPRISING A POLYSACCHARIDE, A POLYOL AND SPECIFIC ESTER AND OIL L'OREAL (FR) 2021-10-27 EP disclosed
WO-2021115730-A1 HAIR STYLING COMPOSITION CONTAINING DISACCHARIDES HENKEL AG & CO. KGAA (DE) 2021-06-17 WO disclosed
WO-2021115731-A1 MICROPLASTIC-FREE COMPOSITION HENKEL AG & CO. KGAA (DE) 2021-06-17 WO disclosed
US-10968138-B2 Gypsum slurries with linear polycarboxylate dispersants UNITED STATES GYPSUM COMPANY (US) 2021-04-06 US disclosed
WO-2020128004-A1 COMPOSITION COMPRISING A POLYSACCHARIDE, A POLYOL AND SPECIFIC ESTER AND OIL L'OREAL (FR) 2020-06-25 WO disclosed
US-20200138690-A1 COSMETIC COMPOSITIONS COMPRISING AN ASSOCIATIVE POLYURETHANE AND A HYDROPHOBIC COATED PIGMENT L'OREAL (FR) 2020-05-07 US disclosed
WO-2016198666-A1 HAIR DYEING PROCESS, FREE OF CHEMICAL OXIDIZING AGENT, USING A TITANIUM SALT AND A DYE L'OREAL (FR) 2016-12-15 WO disclosed
US-20160120788-A1 COSMETIC COMPOSITIONS COMPRISING AN ASSOCIATIVE POLYURETHANE AND A HYDROPHOBIC COATED PIGMENT L'OREAL (FR) 2016-05-05 US disclosed
EP-3003491-A1 COSMETIC COMPOSITIONS COMPRISING AN ASSOCIATIVE POLYURETHANE AND A HYDROPHOBIC COATED PIGMENT L'OREAL (FR) 2016-04-13 EP disclosed
US-20150231054-A1 COPOLYMERS IN COSMETIC COMPOSITIONS COATEX (FR) 2015-08-20 US disclosed
WO-2014195265-A1 COSMETIC COMPOSITIONS COMPRISING AN ASSOCIATIVE POLYURETHANE AND A HYDROPHOBIC COATED PIGMENT L'OREAL (FR) 2014-12-11 WO disclosed
EP-1109750-A4 PROCESS FOR THE INHIBITION OF SCALE IN HARSH SYSTEMS AND NOVEL ANTISCALANTS FOR SAME NALCO CHEMICAL CO (US) 2001-12-05 EP disclosed
EP-1109750-A1 PROCESS FOR THE INHIBITION OF SCALE IN HARSH SYSTEMS AND NOVEL ANTISCALANTS FOR SAME NALCO CHEMICAL COMPANY (US) 2001-06-27 EP disclosed
WO-2000012436-A1 PROCESS FOR THE INHIBITION OF SCALE IN HARSH SYSTEMS AND NOVEL ANTISCALANTS FOR SAME NALCO CHEMICAL COMPANY (US) 2000-03-09 WO disclosed
WO-1995027826-A1 PRE-PASTED WALLCOVERINGS AND THEIR PRODUCTION ALLIED COLLOIDS LIMITED (GB) 1995-10-19 WO disclosed
EP-0376758-A2 Hydrophobically associating polymers EXXON RESEARCH AND ENGINEERING COMPANY (US) 1990-07-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200138690-A1 COSMETIC COMPOSITIONS COMPRISING AN ASSOCIATIVE POLYURETHANE AND A HYDROPHOBIC COATED PIGMENT MC1R, MCHR1, NACA TSHR 377/4885ALDH1A1 1667/4885MAPK1 2895/4885
US-20160120788-A1 COSMETIC COMPOSITIONS COMPRISING AN ASSOCIATIVE POLYURETHANE AND A HYDROPHOBIC COATED PIGMENT MC1R, MCHR1, NACA TSHR 377/4885ALDH1A1 1667/4885MAPK1 2895/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.