Methacrylic Acid

Methacrylic Acid

SCHEMBL4620872

C=C(C)C(=O)O.C=CC(=O)NCC(C)C

nearest known ligand 0.48

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.48
ALDH1A1 P00352 1/20 0.48
MAPK1 P28482 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
CYP2C19 P33261 2/20 0.47
CYP2D6 P10635 1/20 0.47
CNR2 P34972 5/20 0.39
CNR1 P21554 3/20 0.39
PPARG P37231 2/20 0.39
PPARD Q03181 2/20 0.39
PPARA Q07869 2/20 0.39
ZDHHC20 Q5W0Z9 1/20 0.38
ZDHHC2 Q9UIJ5 1/20 0.38
MMP1 P03956 1/20 0.37
MMP8 P22894 1/20 0.37
CETP P11597 1/20 0.37
MAPT P10636 1/20 0.36
HPGD P15428 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
ALOX15 P16050 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL372689 0.88
SCHEMBL7744606 0.86 TSHR (0.52) TSHRALDH1A1MAPK1TDP1CYP2C19
SCHEMBL29770830 0.86 TSHR (0.52) TSHRALDH1A1MAPK1TDP1CYP2C19
Acrylic Acid SCHEMBL20528130 0.85 CYP2D6 (0.50) TSHRALDH1A1MAPK1TDP1CYP2C19
Formic Acid SCHEMBL28269716 0.82 TSHR (0.48) TSHRALDH1A1MAPK1TDP1CYP2C19
Methacrylic Acid SCHEMBL25360380 0.82 ALDH1A1 (0.73) TSHRALDH1A1MAPK1TDP1CYP2C19
Methacrylic Acid SCHEMBL9240421 0.82 ALDH1A1 (0.73) TSHRALDH1A1MAPK1TDP1CYP2C19
Sulfuric Acid SCHEMBL182294 0.81 CYP2D6 (0.50) TSHRALDH1A1MAPK1TDP1CYP2C19
Acrylamide SCHEMBL6553344 0.81 TSHR (0.46) TSHRALDH1A1MAPK1TDP1CYP2C19
Phosphonic Acid SCHEMBL28266598 0.81 TSHR (0.46) TSHRALDH1A1MAPK1TDP1CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1888175-A1 HAIR FIXING COMPOSITION BASED ON BREATHABLE POLYURETHANES Lubrizol Advanced Materials, Inc. (US) 2008-02-20 EP disclosed
WO-2006124250-A1 HAIR FIXING COMPOSITION BASED ON BREATHABLE POLYURETHANES LUBRIZOL ADVANCED MATERIALS, INC. (US) 2006-11-23 WO disclosed