Bisphenol A

Bisphenol A

SCHEMBL7744724

CC(C)(C)c1cc(C(C)(C)c2ccc(O)c(C(C)(C)C)c2)ccc1O.CC(C)(c1ccc(O)cc1)c1ccc(O)cc1

nearest known ligand 0.64

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.64
ALOX15 P16050 4/20 0.64
HSD17B10 Q99714 3/20 0.64
LMNA P02545 2/20 0.64
TYR P14679 2/20 0.64
NR1I2 O75469 1/20 0.64
CYP2C9 P11712 1/20 0.64
MIF P14174 1/20 0.64
HTT P42858 1/20 0.64
NFE2L2 Q16236 1/20 0.64
ESR1 P03372 8/20 0.61
ESR2 Q92731 5/20 0.61
CYP3A4 P08684 2/20 0.61
HPGD P15428 2/20 0.61
TSHR P16473 2/20 0.61
AR P10275 1/20 0.61
SLC6A2 P23975 1/20 0.61
SLC6A4 P31645 1/20 0.61
HTR6 P50406 1/20 0.61
ESRRG P62508 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29515859 1.00 ALDH1A1 (0.64) ALDH1A1ALOX15HSD17B10LMNATYR
SCHEMBL9617582 1.00 ALDH1A1 (0.64) ALDH1A1ALOX15HSD17B10LMNATYR
SCHEMBL29352462 0.92 ALDH1A1 (0.61) ALDH1A1ALOX15HSD17B10LMNATYR
SCHEMBL122974 0.92 ALDH1A1 (0.61) ALDH1A1ALOX15HSD17B10LMNATYR
SCHEMBL29377969 0.92 ALDH1A1 (0.61) ALDH1A1ALOX15HSD17B10LMNATYR
SCHEMBL18494 0.90 ESR1 (0.64) ALDH1A1ALOX15HSD17B10LMNATYR
SCHEMBL7705085 0.87 ESR1 (0.57) ALDH1A1ALOX15HSD17B10LMNATYR
SCHEMBL30301293 0.87 ESR1 (0.59) ALDH1A1ALOX15HSD17B10LMNATYR
SCHEMBL8855209 0.87 ALDH1A1 (0.53) ALDH1A1ALOX15HSD17B10LMNATYR
SCHEMBL9719341 0.87 ALDH1A1 (0.53) ALDH1A1ALOX15HSD17B10LMNATYR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6274682-B1 BLEND CONTAINING POLYAMIDE HEXION INC. (FORMERLY KNOWN AS MOMENTIVE SPECIALTY CHEMICALS INC.) 2001-08-14 US disclosed
US-6180727-B1 TWO COMPONENT CURABLE COMPOSITION COMPRISING AN EPOXY RESIN COMPONENT AND A CURING AGENT COMPRISING THE REACTION PRODUCT OF HYDROCARBYL-SUBSTITUTED HYDROXYBENZOIC ACID, A POLYEPOXIDE COMPOUND, A POLYAMINE AND MONOGLYCIDYL CAPPING AGENT SHELL OIL COMPANY 2001-01-30 US disclosed