Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 3/20 | 0.47 |
| ▸ | PTGER1 | P34995 | 5/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3059005 | 0.89 | SLC22A12 (0.55) | SLC22A12PTGER1 | |
| SCHEMBL7744750 | 0.87 | SLC22A12 (0.48) | SLC22A12PTGER1 | |
| O-Tolylamine SCHEMBL7744406 | 0.85 | PTGER1 (0.49) | SLC22A12PTGER1GAA | |
| SCHEMBL7744400 | 0.83 | SLC22A12 (0.51) | SLC22A12PTGER1 | |
| SCHEMBL1899144 | 0.78 | AURKA (0.56) | PTGER1 | |
| SCHEMBL7744713 | 0.77 | KMT2A (0.62) | PTGER1 | |
| SCHEMBL7744403 | 0.74 | MEN1 (0.66) | PTGER1 | |
| SCHEMBL1137143 | 0.73 | PTGER1 (0.59) | PTGER1 | |
| SCHEMBL2077298 | 0.72 | MEN1 (0.62) | PTGER1 | |
| SCHEMBL18295022 | 0.72 | PTGER1 (0.64) | PTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1252156-A1 | BLOCKADE OF VOLTAGE DEPENDENT SODIUM CHANNELS | University College London (GB) | 2002-10-30 | — | — | EP | disclosed |
| WO-2001057024-A1 | BLOCKADE OF VOLTAGE DEPENDENT SODIUM CHANNELS | UNIVERSITY COLLEGE LONDON (GB) | 2001-08-09 | — | — | WO | disclosed |