Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Nitric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA5A | P35218 | 1/20 | 0.80 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.80 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nitric Acid SCHEMBL6348950 | 1.00 | — | — | |
| Nitric Acid SCHEMBL148735 | 1.00 | — | — | |
| Nitric Acid SCHEMBL5375236 | 1.00 | CA5A (0.80) | CA5ACA5BMEN1KMT2AALDH1A1 | |
| Nitric Acid SCHEMBL8370973 | 0.95 | CA5A (0.73) | CA5ACA5BMEN1KMT2AALDH1A1 | |
| Nitric Acid SCHEMBL5058452 | 0.95 | — | — | |
| Nitric Acid SCHEMBL29004595 | 0.95 | CA5A (0.73) | CA5ACA5BMEN1KMT2AALDH1A1 | |
| Nitric Acid SCHEMBL8369102 | 0.95 | — | — | |
| Nitric Acid SCHEMBL28531290 | 0.95 | CA5A (0.73) | CA5ACA5BMEN1KMT2AALDH1A1 | |
| Nitric Acid SCHEMBL28408464 | 0.91 | — | — | |
| Nitric Acid SCHEMBL8370023 | 0.91 | CA5A (0.67) | CA5ACA5BMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0964843-A4 | GAS GENERANTS COMPRISING TRANSITION METAL NITRITE COMPLEXES | AUTOMOTIVE SYSTEMS LAB (US) | 2001-02-28 | — | — | EP | claimed |
| EP-0964843-A2 | GAS GENERANTS COMPRISING TRANSITION METAL NITRITE COMPLEXES | AUTOMOTIVE SYSTEMS LABORATORY INC. (US) | 1999-12-22 | — | — | EP | claimed |
| WO-1998036938-A2 | GAS GENERANTS COMPRISING TRANSITION METAL NITRITE COMPLEXES | AUTOMOTIVE SYSTEMS LABORATORY, INC. (US) | 1998-08-27 | — | — | WO | claimed |