Thioglycolic Acid

Thioglycolic Acid

SCHEMBL7744974

O=C(O)CS.OC(S)CCS

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 7/20 0.43
ENPEP Q07075 5/20 0.43
ANPEP P15144 3/20 0.43
TET2 Q6N021 3/20 0.33
KDM4A O75164 2/20 0.33
KDM4C Q9H3R0 2/20 0.33
KDM2A Q9Y2K7 2/20 0.33
SLC22A6 Q4U2R8 1/20 0.33
ACE P12821 1/20 0.33
TET3 O43151 1/20 0.33
GSTK1 Q9Y2Q3 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Mercaptopropionic Acid SCHEMBL10335515 0.85 FOLH1 (0.50) FOLH1ENPEPANPEPTET2KDM4A
SCHEMBL94684 0.83
SCHEMBL20471563 0.80
Methyl Alcohol SCHEMBL28730430 0.77
Thioglycolic Acid SCHEMBL4528557 0.75
SCHEMBL7561506 0.73 ANPEP (0.30) FOLH1ENPEPANPEP
Thioglycolic Acid SCHEMBL8166026 0.73 FOLH1 (0.47) FOLH1ENPEPANPEPSLC22A6ACE
Thioglycolic Acid SCHEMBL134322 0.72 LMNA (0.46) FOLH1ENPEPANPEPSLC22A6ACE
Thioglycolic Acid SCHEMBL21017 0.72
Alcohol SCHEMBL29047092 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1040385-A4 THIOGLYCEROL DERIVATIVES AND THEIR USE IN POLYSULFIDE COMPOSITIONS FOR OPTICAL MATERIAL HAMPSHIRE CHEMICAL CORP (US) 2001-01-17 EP disclosed
EP-1040385-A1 THIOGLYCEROL DERIVATIVES AND THEIR USE IN POLYSULFIDE COMPOSITIONS FOR OPTICAL MATERIAL Hampshire Chemical Corporation (US) 2000-10-04 EP disclosed
US-6066758-A HAVE HIGH CONCENTRATIONS OF SULFUR RELATIVE TO COMPOUNDS CONVENTIONALLY USED FOR OPTICAL MATERIALS, AND THUS EXHIBIT HIGH REFRACTIVE INDICES WITHOUT SACRIFICING PROCESSABILITY HAMPSHIRE CHEMICAL CORP. (US) 2000-05-23 US disclosed
US-5973192-A Thioglycerol derivatives and their use in polysulfide compositions for optical material HAMPSHIRE CHEMICAL CORP. (US) 1999-10-26 US disclosed
WO-1999027416-A1 THIOGLYCEROL DERIVATIVES AND THEIR USE IN POLYSULFIDE COMPOSITIONS FOR OPTICAL MATERIAL HAMPSHIRE CHEMICAL CORP. (US) 1999-06-03 WO disclosed