Thioglycolic Acid

Thioglycolic Acid

SCHEMBL7744976

CCC(O)(S)S.O=C(O)CS

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR3 O14843 2/20 0.40
HMGCR P04035 1/20 0.38
CHRM1 P11229 1/20 0.38
TBXA2R P21731 1/20 0.38
ADRA1A P35348 1/20 0.38
HDAC3 O15379 1/20 0.35
HDAC1 Q13547 1/20 0.35
HDAC2 Q92769 1/20 0.35
HDAC8 Q9BY41 1/20 0.35
ALDH1A1 P00352 3/20 0.33
KMT2A Q03164 2/20 0.33
MEN1 O00255 1/20 0.33
CYP1A2 P05177 1/20 0.33
THRB P10828 1/20 0.33
TSHR P16473 3/20 0.32
HSD17B10 Q99714 1/20 0.32
MAPT P10636 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C19 P33261 1/20 0.31
HIF1A Q16665 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Mercaptopropionic Acid SCHEMBL10335516 0.82 ACE (0.46) FFAR3HDAC3HDAC1HDAC2HDAC8
Dimercaprol SCHEMBL27543114 0.82 NR1I2 (0.48) ALDH1A1CYP1A2HSD17B10
Thioglycolic Acid SCHEMBL2672008 0.80 TSHR (0.47) FFAR3HMGCRCHRM1TBXA2RADRA1A
Thioglycolic Acid SCHEMBL10607018 0.78
Thioglycolic Acid SCHEMBL4595079 0.78 FFAR3 (0.53) FFAR3HDAC3HDAC1HDAC2HDAC8
Thioglycolic Acid SCHEMBL16795985 0.78 FFAR3 (0.53) FFAR3HDAC3HDAC1HDAC2HDAC8
Thioglycolic Acid SCHEMBL11854674 0.78
SCHEMBL94682 0.78
Thioglycolic Acid SCHEMBL27606237 0.77 FFAR3 (0.35) FFAR3HMGCRCHRM1TBXA2RADRA1A
Thioglycolic Acid SCHEMBL476547 0.76 FFAR3 (0.50) FFAR3HDAC3HDAC1HDAC2HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1040385-A4 THIOGLYCEROL DERIVATIVES AND THEIR USE IN POLYSULFIDE COMPOSITIONS FOR OPTICAL MATERIAL HAMPSHIRE CHEMICAL CORP (US) 2001-01-17 EP disclosed
EP-1040385-A1 THIOGLYCEROL DERIVATIVES AND THEIR USE IN POLYSULFIDE COMPOSITIONS FOR OPTICAL MATERIAL Hampshire Chemical Corporation (US) 2000-10-04 EP disclosed
US-6066758-A HAVE HIGH CONCENTRATIONS OF SULFUR RELATIVE TO COMPOUNDS CONVENTIONALLY USED FOR OPTICAL MATERIALS, AND THUS EXHIBIT HIGH REFRACTIVE INDICES WITHOUT SACRIFICING PROCESSABILITY HAMPSHIRE CHEMICAL CORP. (US) 2000-05-23 US disclosed
US-5973192-A Thioglycerol derivatives and their use in polysulfide compositions for optical material HAMPSHIRE CHEMICAL CORP. (US) 1999-10-26 US disclosed
WO-1999027416-A1 THIOGLYCEROL DERIVATIVES AND THEIR USE IN POLYSULFIDE COMPOSITIONS FOR OPTICAL MATERIAL HAMPSHIRE CHEMICAL CORP. (US) 1999-06-03 WO disclosed