Styrene

Styrene

SCHEMBL7744977

C=C(C)C(=O)O.C=Cc1ccccc1.N#CC=CC=Cc1ccccc1

nearest known ligand 0.46

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.46
MCL1 Q07820 2/20 0.40
GLA P06280 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
ALDH1A1 P00352 3/20 0.39
MAOB P27338 3/20 0.39
TSHR P16473 1/20 0.39
HDAC3 O15379 2/20 0.39
HDAC4 P56524 2/20 0.39
HDAC1 Q13547 2/20 0.39
HDAC7 Q8WUI4 2/20 0.39
HDAC2 Q92769 2/20 0.39
HDAC10 Q969S8 2/20 0.39
HDAC11 Q96DB2 2/20 0.39
HDAC8 Q9BY41 2/20 0.39
HDAC6 Q9UBN7 2/20 0.39
HDAC9 Q9UKV0 2/20 0.39
HDAC5 Q9UQL6 2/20 0.39
LMNA P02545 3/20 0.37
HTT P42858 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL10702189 0.95 CYP3A4 (0.42) CYP3A4MCL1GLATDP1ALDH1A1
Methacrylic Acid SCHEMBL6906597 0.94 CYP3A4 (0.46) CYP3A4MCL1GLATDP1ALDH1A1
Methacrylic Acid SCHEMBL437865 0.94 CYP3A4 (0.46) CYP3A4MCL1GLATDP1ALDH1A1
Methacrylic Acid SCHEMBL863641 0.93 CYP3A4 (0.43) CYP3A4MCL1GLATDP1ALDH1A1
Methacrylic Acid SCHEMBL28068002 0.93 CYP3A4 (0.45) CYP3A4MCL1GLATDP1ALDH1A1
Styrene SCHEMBL9722971 0.89 CYP3A4 (0.41) CYP3A4MCL1GLATDP1ALDH1A1
Methacrylic Acid SCHEMBL1035064 0.88 CYP3A4 (0.41) CYP3A4MCL1GLATDP1ALDH1A1
Methacrylic Acid SCHEMBL28633225 0.87 CYP3A4 (0.45) CYP3A4MCL1GLATDP1ALDH1A1
Styrene SCHEMBL2710003 0.87 ALDH1A1 (0.52) CYP3A4MCL1ALDH1A1MAOBTSHR
SCHEMBL11422112 0.85 GLA (0.47) CYP3A4MCL1GLATDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001021303-A1 AN IMPROVED METHOD AND APPARATUS FOR DEVOLATILIZATION THE DOW CHEMICAL COMPANY (US) 2001-03-29 WO disclosed
US-4952672-A Method for the devolatilization of thermoplastic materials THE DOW CHEMICAL COMPANY (US) 1990-08-28 US disclosed