Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 9/20 | 0.70 |
| ▸ | CES1 | P23141 | 9/20 | 0.70 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | ALB | P02768 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
| ▸ | MAP2K2 | P36507 | 2/20 | 0.34 |
| ▸ | MAP2K1 | Q02750 | 2/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1760850 | 0.82 | CES2 (0.73) | CES2CES1BCHEALDH1A1MAP2K2 | |
| SCHEMBL11258183 | 0.81 | CES2 (0.52) | CES2CES1BCHEALDH1A1ALB | |
| SCHEMBL4444760 | 0.80 | CES2 (0.70) | CES2CES1BCHEALDH1A1MAP2K2 | |
| SCHEMBL241797 | 0.80 | CES2 (0.70) | CES2CES1BCHEALDH1A1ALB | |
| SCHEMBL9693756 | 0.79 | CES2 (0.45) | CES2CES1BCHEALDH1A1ALOX15 | |
| SCHEMBL7749586 | 0.79 | CES2 (0.50) | CES2CES1BCHEALDH1A1MAP2K1 | |
| SCHEMBL145728 | 0.79 | CES2 (0.61) | CES2CES1BCHEALDH1A1 | |
| SCHEMBL5301076 | 0.78 | CES2 (0.67) | CES2CES1BCHEALDH1A1ALB | |
| SCHEMBL1003016 | 0.78 | CES2 (0.67) | CES2CES1BCHEALDH1A1MAP2K2 | |
| Hydrochloric Acid SCHEMBL4730575 | 0.78 | CES2 (0.67) | CES2CES1BCHEALDH1A1ALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1328238-C | Preparation of 2,4,5-trifluo-benzoic acid | LUYUAN PHARMACEUTICAL CO LTD D (CN) | 2007-07-25 | — | — | CN | claimed |
| CN-1746146-A | Preparation of 2,4,5-trifluo-benzoic acid | LUYUAN PHARMACEUTICAL CO LTD D (CN) | 2006-03-15 | — | — | CN | claimed |
| CN-1119324-C | 3-cyano-2, 4, 5-trifluorobenzoyl fluoride and intermediates for its preparation | BAYER AG (DE) | 2003-08-27 | — | — | CN | claimed |
| CN-1252789-A | 3-cyano-2, 4, 5-trifluorobenzoyl fluoride and intermediates for its preparation | BAYER AG (DE) | 2000-05-10 | — | — | CN | claimed |
| CN-1328238-C | Preparation of 2,4,5-trifluo-benzoic acid | LUYUAN PHARMACEUTICAL CO LTD D (CN) | 2007-07-25 | — | — | CN | disclosed |
| CN-1746146-A | Preparation of 2,4,5-trifluo-benzoic acid | LUYUAN PHARMACEUTICAL CO LTD D (CN) | 2006-03-15 | — | — | CN | disclosed |
| CN-1216040-C | 3-Cyan-2,4,5-trifluoro-benzene formyl fluorine and intermediate produced therefor | BAYER AG (DE) | 2005-08-24 | — | — | CN | disclosed |
| CN-1119324-C | 3-cyano-2, 4, 5-trifluorobenzoyl fluoride and intermediates for its preparation | BAYER AG (DE) | 2003-08-27 | — | — | CN | disclosed |
| CN-1436771-A | 3-Cyan-2,4,5-trifluoro-benzene formyl fluorine and intermediate produced therefor | BAYER AG (DE) | 2003-08-20 | — | — | CN | disclosed |
| EP-0781757-B1 | Process for the preparation of fluorinated benzoic acids | ABBOTT LAB (US) | 2001-01-03 | — | — | EP | disclosed |
| CN-1252789-A | 3-cyano-2, 4, 5-trifluorobenzoyl fluoride and intermediates for its preparation | BAYER AG (DE) | 2000-05-10 | — | — | CN | disclosed |
| US-5859298-A | REACTING 2,4-DICHLORO-5-FLUORO-BENZOYL CHLORIDE WITH POTASSIUM FLUORIDE IN AN APROTIC SOLVENT; DISTILLATION | BAYER AKTIENGESELLSCHAFT (DE) | 1999-01-12 | — | — | US | disclosed |
| CN-1013370-B | Process for preparing derivatives of 2, 4, 5-trihalobenzenes and 2, 3, 4, 5-tetrahalobenzenes | BAYER AG (DE) | 1991-07-31 | — | — | CN | disclosed |
| CN-1007977-B | PROCESS FOR THE PREPARATION OF 7-AMINO-1-CYCLOPXOPYL-6, 8-DIHALOGENO-1, 4-DIHYDRO-4-OXO-3-QUINOLINECARBOXYLIC ACIDS | BAYER AG (DE) | 1990-05-16 | — | — | CN | disclosed |
| US-4868347-A | SOLVENT EXTRACTION | BAYER AKTIENGESELLSCHAFT (DE) | 1989-09-19 | — | — | US | disclosed |
| CN-87107230-A | Quinoline carboxylic acid's method for making | — | 1988-07-06 | — | — | CN | disclosed |
| EP-0270964-A2 | Process for obtaining substituted fluorobenzenes | BAYER AG (DE) | 1988-06-15 | — | — | EP | disclosed |
| CN-85101832-A | The method for preparing 7-(3-aryl-1-piperazinyl)-3-quinolone carboxylic acid and 7-(3-encircles ethyl-1-piperazinyl)-3-quinolone carboxylic acid | — | 1987-01-31 | — | — | CN | disclosed |
| EP-0038223-B1 | PROCESS FOR THE PREPARATION OF TRIFLUOROMETHYLBENZOYL HALIDES | OCCIDENTAL CHEMICAL CORPORATION (US) | 1984-08-08 | — | — | EP | disclosed |
| EP-0038223-A1 | Process for the preparation of trifluoromethylbenzoyl halides | OCCIDENTAL CHEMICAL CORPORATION (US) | 1981-10-21 | — | — | EP | disclosed |