Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AB1 | P08238 | 7/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 6/20 | 0.51 |
| ▸ | CCNE1 | P24864 | 4/20 | 0.47 |
| ▸ | CDK2 | P24941 | 4/20 | 0.47 |
| ▸ | CDK1 | P06493 | 3/20 | 0.47 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.47 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.43 |
| ▸ | AHCY | P23526 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5930393 | 0.87 | HSP90AA1 (0.49) | HSP90AB1HSP90AA1CCNE1CDK2CDK1 | |
| SCHEMBL17364319 | 0.83 | CDK1 (0.67) | HSP90AB1HSP90AA1CCNE1CDK2CDK1 | |
| SCHEMBL9583704 | 0.82 | MEN1 (0.57) | HSP90AB1HSP90AA1CCNE1CDK2CDK1 | |
| SCHEMBL14659477 | 0.82 | HSP90AB1 (0.49) | HSP90AB1HSP90AA1CCNE1CDK2CDK1 | |
| SCHEMBL7749494 | 0.82 | CCNE1 (0.65) | HSP90AB1HSP90AA1CCNE1CDK2CDK1 | |
| SCHEMBL25500746 | 0.81 | MGMT (0.55) | CCNE1CDK2CDK1CCNB1SLC29A1 | |
| SCHEMBL21162268 | 0.80 | HSP90AA1 (0.47) | HSP90AB1HSP90AA1CCNE1CDK2CDK1 | |
| SCHEMBL10509135 | 0.80 | CCNE1 (0.41) | HSP90AB1HSP90AA1CCNE1CDK2CDK1 | |
| SCHEMBL16812182 | 0.80 | HPRT1 (0.52) | HSP90AB1HSP90AA1CCNE1CDK2SLC29A1 | |
| SCHEMBL7749502 | 0.80 | CCNE1 (0.47) | HSP90AB1HSP90AA1CCNE1CDK2CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1019404-A4 | PURINE ACYCLONUCLEOSIDES AS ANTIVIRAL AGENTS | COMMW SCIENT IND RES ORG (AU) | 2001-07-04 | — | — | EP | disclosed |
| EP-1019404-A1 | PURINE ACYCLONUCLEOSIDES AS ANTIVIRAL AGENTS | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2000-07-19 | — | — | EP | disclosed |
| WO-1999012927-A1 | PURINE ACYCLONUCLEOSIDES AS ANTIVIRAL AGENTS | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 1999-03-18 | — | — | WO | disclosed |