Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 4/20 | 0.65 |
| ▸ | CDK2 | P24941 | 4/20 | 0.65 |
| ▸ | CDK1 | P06493 | 3/20 | 0.65 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.65 |
| ▸ | AHCY | P23526 | 3/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.44 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4570450 | 0.92 | CCNE1 (0.58) | CCNE1CDK2CDK1CCNB1AHCY | |
| SCHEMBL23710566 | 0.87 | AHCY (0.68) | CCNE1CDK2CDK1CCNB1AHCY | |
| SCHEMBL7749633 | 0.86 | CDK2 (0.48) | CCNE1CDK2CDK1CCNB1AHCY | |
| SCHEMBL7749502 | 0.85 | CCNE1 (0.47) | CCNE1CDK2CDK1CCNB1AHCY | |
| SCHEMBL5930210 | 0.85 | CCNE1 (0.61) | CCNE1CDK2CDK1CCNB1AHCY | |
| SCHEMBL22300666 | 0.82 | CCNE1 (0.70) | CCNE1CDK2CDK1CCNB1AHCY | |
| SCHEMBL12964251 | 0.82 | CCNE1 (0.57) | CCNE1CDK2CDK1CCNB1AHCY | |
| SCHEMBL7745006 | 0.82 | HSP90AB1 (0.51) | CCNE1CDK2CDK1CCNB1AHCY | |
| SCHEMBL7263234 | 0.82 | ADORA2A (0.67) | CCNE1CDK2CDK1CCNB1AHCY | |
| SCHEMBL7263232 | 0.82 | ADORA2A (0.67) | CCNE1CDK2CDK1CCNB1AHCY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1019404-A4 | PURINE ACYCLONUCLEOSIDES AS ANTIVIRAL AGENTS | COMMW SCIENT IND RES ORG (AU) | 2001-07-04 | — | — | EP | disclosed |
| EP-1019404-A1 | PURINE ACYCLONUCLEOSIDES AS ANTIVIRAL AGENTS | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2000-07-19 | — | — | EP | disclosed |
| WO-1999012927-A1 | PURINE ACYCLONUCLEOSIDES AS ANTIVIRAL AGENTS | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 1999-03-18 | — | — | WO | disclosed |