⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8525696 | 0.78 | — | — | |
| SCHEMBL6036787 | 0.77 | — | — | |
| SCHEMBL25686595 | 0.77 | — | — | |
| SCHEMBL25686596 | 0.77 | — | — | |
| SCHEMBL17472512 | 0.74 | — | — | |
| SCHEMBL6561447 | 0.71 | ALDH1A1 (0.33) | — | |
| SCHEMBL10998137 | 0.70 | MAPT (0.34) | — | |
| SCHEMBL7751136 | 0.70 | — | — | |
| SCHEMBL411529 | 0.70 | POLB (0.49) | — | |
| SCHEMBL11917921 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0780450-B1 | Aqueous ink compositions containing amide anti-curl agent | DU PONT (US) | 2001-05-23 | — | — | EP | claimed |
| EP-0780450-A2 | Aqueous ink compositions containing amide anti-curl agent | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1997-06-25 | — | — | EP | claimed |
| US-5580373-A | Aqueous ink compositions containing amide anti-curl agent | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1996-12-03 | — | — | US | claimed |
| EP-3307741-B1 | POSITIVE ALLOSTERIC MODULATORS OF THE MUSCARIC M2 RECEPTOR | Bayer Pharma AG (DE) | 2020-10-28 | — | — | EP | disclosed |
| EP-3692991-A1 | POSITIVE ALLOSTERIC MODULATORS OF THE MUSCARINIC M2 RECEPTOR | Bayer Pharma Aktiengesellschaft (DE) | 2020-08-12 | — | — | EP | disclosed |
| US-10435403-B2 | Positive allosteric modulators of muscarinic M2 receptor | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2019-10-08 | — | — | US | disclosed |
| US-20180297994-A1 | POSITIVE ALLOSTERIC MODULATORS OF MUSCARINIC M2 RECEPTOR | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2018-10-18 | — | — | US | disclosed |
| EP-3307741-A1 | POSITIVE ALLOSTERIC MODULATORS OF MUSCARINIC M2 RECEPTOR | Bayer Pharma Aktiengesellschaft (DE) | 2018-04-18 | — | — | EP | disclosed |
| WO-2016198342-A1 | POSITIVE ALLOSTERIC MODULATORS OF MUSCARINIC M2 RECEPTOR | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2016-12-15 | — | — | WO | disclosed |
| EP-0780450-B1 | Aqueous ink compositions containing amide anti-curl agent | DU PONT (US) | 2001-05-23 | — | — | EP | disclosed |
| EP-0780450-A2 | Aqueous ink compositions containing amide anti-curl agent | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1997-06-25 | — | — | EP | disclosed |
| US-5580373-A | Aqueous ink compositions containing amide anti-curl agent | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1996-12-03 | — | — | US | disclosed |