Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.69 |
| ▸ | HTT | P42858 | 2/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.67 |
| ▸ | POLB | P06746 | 2/20 | 0.67 |
| ▸ | PKM | P14618 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 3/20 | 0.65 |
| ▸ | GAA | P10253 | 2/20 | 0.62 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.61 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6198859 | 0.85 | KAT2B (0.80) | MAPTALDH1A1HTTSMN1; SMN2LMNA | |
| SCHEMBL12515298 | 0.81 | KAT2B (0.69) | MAPTALDH1A1HTTSMN1; SMN2LMNA | |
| SCHEMBL10800407 | 0.81 | MAPT (0.63) | MAPTALDH1A1HTTSMN1; SMN2LMNA | |
| SCHEMBL7740648 | 0.81 | KAT2B (0.64) | MAPTALDH1A1HTTSMN1; SMN2POLB | |
| SCHEMBL29709934 | 0.80 | ALDH1A1 (0.53) | MAPTALDH1A1HTTSMN1; SMN2PKM | |
| SCHEMBL1039965 | 0.80 | ALDH1A1 (0.53) | MAPTALDH1A1HTTSMN1; SMN2PKM | |
| SCHEMBL4077151 | 0.79 | KAT2B (0.66) | MAPTALDH1A1HTTSMN1; SMN2PKM | |
| SCHEMBL7170020 | 0.79 | KAT2B (0.81) | MAPTALDH1A1HTTSMN1; SMN2LMNA | |
| SCHEMBL6200169 | 0.79 | KAT2B (0.81) | MAPTALDH1A1HTTSMN1; SMN2LMNA | |
| SCHEMBL7167935 | 0.78 | KAT2B (0.69) | MAPTALDH1A1HTTSMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |