Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.39 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.39 |
| ▸ | CFTR | P13569 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7745618 | 0.77 | MAPK1 (0.55) | TSHRMAPK1MAPTTP53POLB | |
| SCHEMBL7745481 | 0.72 | CNR2 (0.50) | TSHRMAPK1MAPTKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL5858859 | 0.72 | TSHR (0.70) | TSHRMAPK1MAPTTP53POLB | |
| SCHEMBL25251690 | 0.72 | NOS1 (0.57) | NOS1NOS2POLBKMT2AMEN1 | |
| SCHEMBL7740507 | 0.71 | MAPK1 (0.68) | TSHRMAPK1MAPTTP53POLB | |
| SCHEMBL7745460 | 0.71 | TSHR (0.61) | TSHRMAPK1NOS1NOS2MAPT | |
| SCHEMBL5859138 | 0.69 | TSHR (0.65) | TSHRMAPK1MAPTTP53POLB | |
| SCHEMBL14733928 | 0.69 | TSHR (1.00) | TSHRMAPK1MAPTTP53POLB | |
| SCHEMBL7745456 | 0.69 | TSHR (0.61) | TSHRMAPK1NOS1NOS2MAPT | |
| SCHEMBL7745601 | 0.68 | TSHR (0.68) | TSHRMAPK1MAPTTP53POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |