Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.71 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.53 |
| ▸ | KDM1A | O60341 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | SCN1A | P35498 | 1/20 | 0.53 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.53 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14914 | 0.90 | MAPT (0.85) | MAPTNAPRTHSD17B10EPHX2KDM1A | |
| SCHEMBL9121361 | 0.90 | MAPT (0.85) | MAPTNAPRTHSD17B10EPHX2KDM1A | |
| SCHEMBL27538195 | 0.90 | EPHX2 (0.63) | MAPTEPHX2KDM1AGAASCN1A | |
| SCHEMBL28996270 | 0.88 | MAPT (0.82) | MAPTNAPRTHSD17B10EPHX2KDM1A | |
| SCHEMBL8849064 | 0.88 | MAPT (0.82) | MAPTNAPRTHSD17B10EPHX2KDM1A | |
| Bromide SCHEMBL27974437 | 0.88 | MAPT (0.82) | MAPTNAPRTHSD17B10EPHX2KDM1A | |
| Hydrochloric Acid SCHEMBL28406796 | 0.88 | MAPT (0.82) | MAPTNAPRTHSD17B10EPHX2KDM1A | |
| SCHEMBL587369 | 0.88 | MAPT (0.82) | MAPTNAPRTHSD17B10EPHX2KDM1A | |
| Potassium SCHEMBL30309050 | 0.88 | MAPT (0.82) | MAPTNAPRTHSD17B10EPHX2KDM1A | |
| Methane SCHEMBL28009609 | 0.88 | MAPT (0.82) | MAPTNAPRTHSD17B10EPHX2KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160355465-A1 | NOVEL MODIFIED CURCUMINS AND THEIR USES | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2016-12-08 | — | — | US | disclosed |
| US-20140275271-A1 | NOVEL MODIFIED CURCUMINS AND THEIR USES | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2014-09-18 | — | — | US | disclosed |
| EP-2768797-A1 | NOVEL MODIFIED CURCUMINS AND THEIR USES | The Research Foundation Of State University Of New York (US) | 2014-08-27 | — | — | EP | disclosed |
| WO-2013059203-A1 | NOVEL MODIFIED CURCUMINS AND THEIR USES | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2013-04-25 | — | — | WO | disclosed |
| WO-2001000684-A1 | LIQUID OLIGOMERS CONTAINING UNSATURATION | ASHLAND INC. (US) | 2001-01-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160355465-A1 | NOVEL MODIFIED CURCUMINS AND THEIR USES | NFKBIA, NFKB1, NFKB2 | MAPT 4325/4885NAPRT 1948/4885HSD17B10 3122/4885 |
| US-20140275271-A1 | NOVEL MODIFIED CURCUMINS AND THEIR USES | NFKBIA, NFKB1, NFKB2 | MAPT 4325/4885NAPRT 1948/4885HSD17B10 3122/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.