Indene

Indene

SCHEMBL7745309

C1=Cc2ccccc2C1.Cc1ccccc1

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 1/20 0.50
CYP2C19 P33261 1/20 0.50
LMNA P02545 2/20 0.48
TSHR P16473 1/20 0.48
ALOX12 P18054 1/20 0.48
ACHE P22303 1/20 0.48
CA1 P00915 2/20 0.47
CA2 P00918 2/20 0.47
PARP1 P09874 1/20 0.36
HPGD P15428 1/20 0.32
MAOB P27338 2/20 0.31
MAPT P10636 2/20 0.31
ALDH1A1 P00352 1/20 0.31
HSD17B3 P37058 1/20 0.31
POLB P06746 1/20 0.31
CES2 O00748 1/20 0.30
CES1 P23141 1/20 0.30
NPC1 O15118 2/20 0.30
RAB9A P51151 2/20 0.30
NFKB1 P19838 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Indene SCHEMBL29142763 0.89 CA1 (0.46) CYP2D6CYP2C19LMNATSHRALOX12
Indene SCHEMBL8617 0.89
Indene SCHEMBL8336138 0.89 CA1 (0.55) CYP2D6CYP2C19TSHRCA1CA2
Indene SCHEMBL29350094 0.89
Indene SCHEMBL23301011 0.86 CA1 (0.53) CYP2D6CYP2C19TSHRCA1CA2
Indene SCHEMBL7153004 0.86 CA1 (0.53) CYP2D6CYP2C19TSHRCA1CA2
Indene SCHEMBL6285027 0.86 CA1 (0.53) CYP2D6CYP2C19TSHRCA1CA2
Indene SCHEMBL8971559 0.86 CA1 (0.53) CYP2D6CYP2C19TSHRCA1CA2
Indene SCHEMBL8971580 0.86 CA1 (0.53) CYP2D6CYP2C19TSHRCA1CA2
Indene SCHEMBL23071394 0.86 CA1 (0.53) CYP2D6CYP2C19TSHRCA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109476776-B Composite catalyst composition, preparation method thereof and polyolefin prepared by using same 韩华石油化学株式会社 2022-11-25 CN disclosed
CN-109476776-A Composite catalyst composition, preparation method and the polyolefin using its preparation 韩华石油化学株式会社 2019-03-15 CN disclosed
WO-2001040235-A1 PROCESS FOR PRODUCING DI-(TETRAKIS(FLUOROARYL)BORATO)-MAGNESIUM-SALTS AND CLATHRATES ALBEMARLE CORPORATION (US) 2001-06-07 WO disclosed
CN-1194006-A Conversion of indene to (IS) -amino- (2R) -indanol free of any stereoisomer using a combination of dioxygenase biotransformation and chemical steps MERCK & CO INC (US) 1998-09-23 CN disclosed