SCHEMBL7745492

SCHEMBL7745492

CC1CCC(=O)CC(C)(C)C1

nearest known ligand 0.35

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.35
CRBN Q96SW2 1/20 0.34
ALDH1A1 P00352 4/20 0.34
GAA P10253 2/20 0.33
TDP1 Q9NUW8 1/20 0.33
CYP11B2 P19099 1/20 0.32
CYP3A4 P08684 1/20 0.32
KDM4E B2RXH2 2/20 0.31
LMNA P02545 1/20 0.31
CYP2C19 P33261 1/20 0.31
GLA P06280 1/20 0.31
TLR4 O00206 1/20 0.30
ALOX15 P16050 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9720093 0.86 ALDH1A1 (0.34) CRBNALDH1A1GAATDP1
SCHEMBL27781831 0.77 ALDH1A1 (0.42) MAPTCRBNALDH1A1GAATDP1
SCHEMBL4868570 0.77 ALDH1A1 (0.42) MAPTCRBNALDH1A1GAATDP1
SCHEMBL24862 0.77 ALDH1A1 (0.42) MAPTCRBNALDH1A1GAATDP1
Water SCHEMBL27960090 0.76 ALDH1A1 (0.41) MAPTCRBNALDH1A1GAATDP1
Ethylene SCHEMBL28206554 0.74 ALDH1A1 (0.41) MAPTCRBNALDH1A1GAATDP1
SCHEMBL104009 0.70
SCHEMBL12856098 0.70 MAPT (0.42) MAPTALDH1A1GAAKDM4EGLA
SCHEMBL27836649 0.70 CRBN (0.41) CRBNALDH1A1TLR4
Sulfuric Acid SCHEMBL28235756 0.69 ALDH1A1 (0.38) MAPTCRBNALDH1A1GAATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108863792-B Comprehensive utilization method of isocoumaene 广东天龙精细化工有限公司 2021-03-23 CN disclosed
EP-0770589-B1 Process for the preparation of bisphenols using new co-catalysts BAYER AG (DE) 2001-01-10 EP disclosed
US-5759752-A TRANSPARENT POLYCARBONATE AGFA-GEVAERT N.V. (BE) 1998-06-02 US disclosed
US-5698600-A Process for the production of bisphenols with the use of new cocatalysts BAYER AG (DE) 1997-12-16 US disclosed
EP-0770589-A2 Process for the preparation of bisphenols using new co-catalysts BAYER AG (DE) 1997-05-02 EP disclosed
EP-0614769-B1 Direct thermal imaging material containing a protective layer AGFA GEVAERT NV (BE) 1996-09-25 EP disclosed
EP-0573086-B1 Dye-donor element for use according to thermal dye sublimation transfer AGFA GEVAERT NV (BE) 1996-03-13 EP disclosed
EP-0402678-B1 Polycarbonate mixtures for optical devices BAYER AG (DE) 1995-11-02 EP disclosed
EP-0523474-B1 Dye receiving sheet for the thermosublimation printing process AGFA GEVAERT AG (DE) 1995-09-20 EP disclosed
EP-0414083-B1 Stabilized polycarbonates BAYER AG (DE) 1995-01-18 EP disclosed
EP-0402678-A2 Polycarbonate mixtures for optical devices BAYER AG (DE) 1990-12-19 EP disclosed
EP-0400409-A2 Aromatic copolyetherketones BAYER AG (DE) 1990-12-05 EP disclosed
EP-0400411-A2 Aromatic polyethersulphones BAYER AG (DE) 1990-12-05 EP disclosed
EP-0393454-A2 Heat-resistant polycarbonate moulding composition BAYER AG (DE) 1990-10-24 EP disclosed
US-4964890-A GAS-PERMEABLE FILMS OF A THERMOPLASTIC POLYETHER HAVING DIHYDROXYBENZOPHENONE AND DIHYDROXYDIPHENYLCYCLOALKANE UNITS; DIMENSIONAL STABILITY; HEAT RESISTANCE; MEMBRANES BAYER AKTIENGESELLSCHAFT (DE) 1990-10-23 US disclosed
EP-0365917-A1 Polymer mixtures BAYER AG (DE) 1990-05-02 EP disclosed
EP-0365916-A1 Polymer mixtures BAYER AG (DE) 1990-05-02 EP disclosed
EP-0364741-A1 Aromatic polyetherketones BAYER AG (DE) 1990-04-25 EP disclosed
EP-0362603-A1 Aromatic Polyethersulfones BAYER AG (DE) 1990-04-11 EP disclosed
EP-0359953-A1 Dihydroxydiphenylcycloalkanes, their preparation and their use for the preparation of high molecular polycarbonates BAYER AG (DE) 1990-03-28 EP disclosed