Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.68 |
| ▸ | ACE | P12821 | 4/20 | 0.67 |
| ▸ | ITGB2 | P05107 | 7/20 | 0.66 |
| ▸ | ICAM1 | P05362 | 7/20 | 0.66 |
| ▸ | ITGAL | P20701 | 7/20 | 0.66 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.65 |
| ▸ | FPR2 | P25090 | 1/20 | 0.65 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11369495 | 1.00 | ALOX15 (0.68) | ALOX15ACEITGB2ICAM1ITGAL | |
| SCHEMBL6426552 | 1.00 | ALOX15 (0.68) | ALOX15ACEITGB2ICAM1ITGAL | |
| SCHEMBL30936746 | 0.88 | ALOX15 (0.70) | ALOX15ACEITGB2ICAM1ITGAL | |
| SCHEMBL13278205 | 0.88 | ALOX15 (0.70) | ALOX15ACEITGB2ICAM1ITGAL | |
| SCHEMBL29987387 | 0.88 | ALOX15 (0.70) | ALOX15ACEITGB2ICAM1ITGAL | |
| SCHEMBL6313468 | 0.88 | ALOX15 (0.70) | ALOX15ACEITGB2ICAM1ITGAL | |
| SCHEMBL1994982 | 0.88 | ALOX15 (0.70) | ALOX15ACEITGB2ICAM1ITGAL | |
| SCHEMBL1994981 | 0.88 | ALOX15 (0.70) | ALOX15ACEITGB2ICAM1ITGAL | |
| SCHEMBL3728145 | 0.88 | ALOX15 (0.70) | ALOX15ACEITGB2ICAM1ITGAL | |
| SCHEMBL1407979 | 0.87 | ALOX15 (0.68) | ALOX15ACEITGB2ICAM1ITGAL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0819005-A4 | 2-ACYLAMINOPROPANAMIDES AS TACHYKININ RECEPTOR ANTAGONISTS | LILLY CO ELI (US) | 2001-03-21 | — | — | EP | disclosed |
| EP-0819005-A1 | 2-ACYLAMINOPROPANAMIDES AS TACHYKININ RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1998-01-21 | — | — | EP | disclosed |
| WO-1996031214-A1 | 2-ACYLAMINOPROPANAMIDES AS TACHYKININ RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1996-10-10 | — | — | WO | disclosed |
| US-4283337-A | Process for the purification of tryptophane and derivatives of tryptophane | DEUTSCHE GOLD UND- SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) | 1981-08-11 | — | — | US | disclosed |