Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 6/20 | 0.47 |
| ▸ | TBXA2R | P21731 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.43 |
| ▸ | RORC | P51449 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7745027 | 0.85 | TSHR (0.58) | F2RL3TSHRMAPK1ALDH1A1HPGD | |
| SCHEMBL7745456 | 0.75 | TSHR (0.61) | TSHRMAPK1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL7745460 | 0.75 | TSHR (0.61) | TSHRMAPK1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL4483857 | 0.74 | F2RL3 (0.67) | F2RL3DRD2TBXA2RALDH1A1HPGD | |
| SCHEMBL4478044 | 0.73 | F2RL3 (0.57) | F2RL3TSHRMAPK1ALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL5858859 | 0.72 | TSHR (0.70) | TSHRMAPK1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL7740752 | 0.71 | DRD2 (0.44) | TSHRMAPK1DRD2TBXA2RALDH1A1 | |
| SCHEMBL6218696 | 0.71 | CNR2 (0.48) | TSHRMAPK1DRD2TBXA2RALDH1A1 | |
| SCHEMBL6216920 | 0.70 | CNR2 (0.68) | CNR2KDM4E | |
| SCHEMBL7745216 | 0.70 | TSHR (0.50) | TSHRMAPK1ALDH1A1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |