Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.32 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.31 |
| ▸ | MLNR | O43193 | 1/20 | 0.31 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7745671 | 1.00 | PTPN1 (0.37) | PTPN1CHRM1CHRM3CHRM2CHRM4 | |
| SCHEMBL7745660 | 1.00 | PTPN1 (0.37) | PTPN1CHRM1CHRM3CHRM2CHRM4 | |
| SCHEMBL8009961 | 0.96 | ADORA1 (0.33) | PTPN1CHRM1CHRM3CHRM2CHRM4 | |
| SCHEMBL5003030 | 0.96 | ADORA1 (0.33) | PTPN1CHRM1CHRM3CHRM2CHRM4 | |
| SCHEMBL8009972 | 0.96 | ADORA1 (0.33) | PTPN1CHRM1CHRM3CHRM2CHRM4 | |
| SCHEMBL7750522 | 0.94 | ADORA1 (0.34) | PTPN1CHRM1CHRM3CHRM2CHRM4 | |
| SCHEMBL7750517 | 0.94 | ADORA1 (0.34) | PTPN1CHRM1CHRM3CHRM2CHRM4 | |
| SCHEMBL7750523 | 0.94 | ADORA1 (0.34) | PTPN1CHRM1CHRM3CHRM2CHRM4 | |
| SCHEMBL7745631 | 0.93 | CHRM1 (0.34) | PTPN1CHRM1CHRM3CHRM2CHRM4 | |
| SCHEMBL7745635 | 0.93 | CHRM1 (0.34) | PTPN1CHRM1CHRM3CHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0898596-B1 | SQUARATE DYES AND THEIR USE IN FLUORESCENT SEQUENCING METHOD | AMERSHAM PHARM BIOTECH UK LTD (GB) | 2001-08-29 | — | — | EP | disclosed |
| US-6140494-A | INCREASED WATER SOLUBILITY, INCREASED PHOTOSTABILITY, BRIGHTNESS AND THE POTENTIAL REDUCTION OF INTERACTIONS WITH SURROUNDINGS | AMERSHAM PHARMACIA BIOTECH UK LIMITED (GB) | 2000-10-31 | — | — | US | disclosed |