Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | TP53 | P04637 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7740951 | 0.83 | TSHR (0.56) | TSHRMAPK1LMNAMAPTMEN1 | |
| SCHEMBL7745601 | 0.82 | TSHR (0.68) | TSHRMAPK1LMNAMAPTMEN1 | |
| SCHEMBL7740507 | 0.82 | MAPK1 (0.68) | TSHRMAPK1LMNAMAPTMEN1 | |
| Hydrochloric Acid SCHEMBL5858859 | 0.80 | TSHR (0.70) | TSHRMAPK1LMNAMAPTMEN1 | |
| SCHEMBL14733928 | 0.79 | TSHR (1.00) | TSHRMAPK1LMNAMAPTMEN1 | |
| SCHEMBL7740380 | 0.78 | MAPK1 (0.76) | TSHRMAPK1LMNAMAPTMEN1 | |
| SCHEMBL7740954 | 0.78 | TSHR (0.76) | TSHRMAPK1LMNAMAPTMEN1 | |
| SCHEMBL3729168 | 0.78 | TSHR (0.76) | TSHRMAPK1LMNAMAPTMEN1 | |
| SCHEMBL5859138 | 0.77 | TSHR (0.65) | TSHRMAPK1LMNAMAPTMEN1 | |
| Hydrochloric Acid SCHEMBL16163295 | 0.77 | TSHR (0.74) | TSHRMAPK1LMNAMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |