Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7745674 | 0.83 | TSHR (0.65) | TSHRMAPK1LMNAKMT2AKDM4E | |
| SCHEMBL7745627 | 0.78 | ALDH1A1 (0.63) | TSHRMAPK1LMNAKMT2AMEN1 | |
| SCHEMBL7740507 | 0.78 | MAPK1 (0.68) | TSHRMAPK1LMNAKMT2AKDM4E | |
| SCHEMBL3825708 | 0.77 | TSHR (0.57) | TSHRMAPK1LMNAKMT2AKDM4E | |
| Hydrochloric Acid SCHEMBL5858859 | 0.76 | TSHR (0.70) | TSHRMAPK1LMNAKMT2AKDM4E | |
| SCHEMBL7745601 | 0.75 | TSHR (0.68) | TSHRMAPK1LMNAKMT2AKDM4E | |
| SCHEMBL7741764 | 0.75 | TSHR (0.52) | TSHRMAPK1KMT2AKDM4EMEN1 | |
| SCHEMBL3822957 | 0.75 | TSHR (0.49) | TSHRMAPK1LMNAKMT2AGAA | |
| SCHEMBL7740380 | 0.74 | MAPK1 (0.76) | TSHRMAPK1LMNAKMT2AKDM4E | |
| Hydrochloric Acid SCHEMBL16163295 | 0.73 | TSHR (0.74) | TSHRMAPK1LMNAKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |