Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 9/20 | 0.53 |
| ▸ | IDO1 | P14902 | 4/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | TTR | P02766 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | TDO2 | P48775 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.48 |
| ▸ | GALR3 | O60755 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10625937 | 1.00 | LRRK2 (0.53) | LRRK2IDO1GAAALDH1A1MAPT | |
| SCHEMBL27319548 | 0.82 | LRRK2 (0.43) | LRRK2IDO1GAAALDH1A1MAPT | |
| SCHEMBL30892354 | 0.81 | LRRK2 (0.59) | LRRK2IDO1GAAALDH1A1MAPT | |
| SCHEMBL30892352 | 0.81 | LRRK2 (0.59) | LRRK2IDO1GAAALDH1A1MAPT | |
| SCHEMBL6317311 | 0.81 | LRRK2 (0.59) | LRRK2IDO1GAAALDH1A1MAPT | |
| SCHEMBL6317313 | 0.81 | LRRK2 (0.59) | LRRK2IDO1GAAALDH1A1MAPT | |
| SCHEMBL7611321 | 0.81 | LRRK2 (0.55) | LRRK2IDO1GAAALDH1A1MAPT | |
| SCHEMBL7611320 | 0.81 | LRRK2 (0.55) | LRRK2IDO1GAAALDH1A1MAPT | |
| SCHEMBL16119559 | 0.78 | AGTR1 (0.43) | LRRK2IDO1GAAALDH1A1MAPT | |
| SCHEMBL22215184 | 0.78 | MAPT (0.39) | LRRK2IDO1GAAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |