Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.41 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.41 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7746011 | 0.92 | GAA (0.49) | LMNATSHRMAPK1GAAPOLB | |
| SCHEMBL7745735 | 0.88 | TSHR (0.49) | LMNATSHRMAPK1GAAPOLB | |
| SCHEMBL7745801 | 0.87 | TSHR (0.43) | LMNATSHRHTTMAPK1GAA | |
| SCHEMBL7741006 | 0.84 | TSHR (0.47) | LMNATSHRHTTMAPK1GAA | |
| SCHEMBL7741104 | 0.80 | TSHR (0.55) | LMNATSHRHTTMAPK1POLB | |
| SCHEMBL3822957 | 0.74 | TSHR (0.49) | LMNATSHRHTTMAPK1GAA | |
| SCHEMBL2880216 | 0.70 | TSHR (0.48) | LMNATSHRMAPK1GAAPOLB | |
| SCHEMBL7740569 | 0.69 | TSHR (0.53) | LMNATSHRMAPK1POLBMEN1 | |
| SCHEMBL16163238 | 0.69 | TSHR (0.53) | TSHRMAPK1 | |
| SCHEMBL7740565 | 0.69 | TSHR (0.43) | LMNATSHRMAPK1GAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |