Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CDC25A | P30304 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7745735 | 0.90 | TSHR (0.49) | TSHRMAPK1ALDH1A1NPSR1MAPT | |
| SCHEMBL7745801 | 0.84 | TSHR (0.43) | TSHRMAPK1ALDH1A1NPSR1MAPT | |
| SCHEMBL7745704 | 0.84 | LMNA (0.43) | TSHRMAPK1HPGDHTTLMNA | |
| SCHEMBL7741104 | 0.84 | TSHR (0.55) | TSHRMAPK1ALDH1A1NPSR1MAPT | |
| SCHEMBL7746011 | 0.82 | GAA (0.49) | TSHRMAPK1ALDH1A1LMNAGAA | |
| SCHEMBL1751915 | 0.73 | CDC25A (0.50) | TSHRALDH1A1KDM4EHPGDCYP1A2 | |
| SCHEMBL2880216 | 0.73 | TSHR (0.48) | TSHRMAPK1ALDH1A1MAPTKDM4E | |
| SCHEMBL7745697 | 0.72 | TSHR (0.64) | TSHRMAPK1ALDH1A1NPSR1MAPT | |
| SCHEMBL7745839 | 0.72 | TSHR (0.52) | TSHRMAPK1ALDH1A1NPSR1MAPT | |
| SCHEMBL7740562 | 0.72 | TSHR (0.57) | TSHRMAPK1ALDH1A1NPSR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |