Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | ENPP1 | P22413 | 4/20 | 0.54 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.54 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.52 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.52 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.52 |
| ▸ | LDHA | P00338 | 1/20 | 0.52 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.52 |
| ▸ | FBP1 | P09467 | 1/20 | 0.52 |
| ▸ | SRC | P12931 | 1/20 | 0.52 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.52 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.52 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.52 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.52 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.52 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8173011 | 0.89 | ADORA1 (0.56) | POLBENPP1P2RY1ADORA1SMN1; SMN2 | |
| SCHEMBL29403419 | 0.89 | ADORA1 (0.56) | POLBENPP1P2RY1ADORA1SMN1; SMN2 | |
| SCHEMBL20327207 | 0.88 | POLB (0.55) | POLBENPP1P2RY1DNPH1PRKAB2 | |
| SCHEMBL20277576 | 0.87 | POLB (0.73) | POLBENPP1P2RY1DNPH1PRKAB2 | |
| SCHEMBL20276952 | 0.87 | POLB (0.73) | POLBENPP1P2RY1DNPH1PRKAB2 | |
| SCHEMBL24059865 | 0.87 | POLB (0.73) | POLBENPP1P2RY1DNPH1PRKAB2 | |
| SCHEMBL30969962 | 0.87 | POLB (0.73) | POLBENPP1P2RY1DNPH1PRKAB2 | |
| SCHEMBL6915410 | 0.87 | POLB (0.73) | POLBENPP1P2RY1DNPH1PRKAB2 | |
| SCHEMBL20282944 | 0.87 | POLB (0.73) | POLBENPP1P2RY1DNPH1PRKAB2 | |
| SCHEMBL22765943 | 0.87 | POLB (0.51) | POLBENPP1P2RY1DNPH1PRKAB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0929218-A4 | P2Y RECEPTOR ANTAGONISTS | UNIV NORTH CAROLINA (US) | 2001-05-16 | — | — | EP | claimed |
| EP-0929218-A2 | P2Y RECEPTOR ANTAGONISTS | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 1999-07-21 | — | — | EP | claimed |
| WO-1998018430-A2 | P2Y RECEPTOR ANTAGONISTS | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 1998-05-07 | — | — | WO | claimed |
| EP-0929218-A4 | P2Y RECEPTOR ANTAGONISTS | UNIV NORTH CAROLINA (US) | 2001-05-16 | — | — | EP | disclosed |
| EP-0929218-A2 | P2Y RECEPTOR ANTAGONISTS | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 1999-07-21 | — | — | EP | disclosed |
| WO-1998018430-A2 | P2Y RECEPTOR ANTAGONISTS | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 1998-05-07 | — | — | WO | disclosed |