SCHEMBL7745797

SCHEMBL7745797

CCCCC=C(C#N)C(=O)OCCCC

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 2/20 0.45
ATM Q13315 1/20 0.43
CYP2C9 P11712 2/20 0.42
ALDH1A1 P00352 2/20 0.41
TSHR P16473 3/20 0.41
HPGD P15428 1/20 0.41
DNM1 Q05193 3/20 0.40
HCAR2 Q8TDS4 1/20 0.39
POLB P06746 2/20 0.37
MAPT P10636 2/20 0.37
MEN1 O00255 1/20 0.37
LMNA P02545 1/20 0.37
CYP3A4 P08684 1/20 0.37
GAA P10253 1/20 0.37
CYP2D6 P10635 1/20 0.37
CYP2C19 P33261 1/20 0.37
KMT2A Q03164 1/20 0.37
PDCD1 Q15116 1/20 0.36
CD274 Q9NZQ7 1/20 0.36
TDP1 Q9NUW8 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7745794 1.00 TP53 (0.45) TP53ATMCYP2C9ALDH1A1TSHR
SCHEMBL7743058 0.95 TP53 (0.44) TP53ATMCYP2C9ALDH1A1TSHR
SCHEMBL7743061 0.95 TP53 (0.44) TP53ATMCYP2C9ALDH1A1TSHR
SCHEMBL7745806 0.94 TSHR (0.44) TP53ATMCYP2C9ALDH1A1TSHR
SCHEMBL7743277 0.94 TSHR (0.44) TP53ATMCYP2C9ALDH1A1TSHR
SCHEMBL7743274 0.94 TSHR (0.44) TP53ATMCYP2C9ALDH1A1TSHR
SCHEMBL7745807 0.94 TSHR (0.44) TP53ATMCYP2C9ALDH1A1TSHR
SCHEMBL7737758 0.93 TP53 (0.45) TP53ATMCYP2C9ALDH1A1TSHR
SCHEMBL7737755 0.93 TP53 (0.45) TP53ATMCYP2C9ALDH1A1TSHR
SCHEMBL7167564 0.91 DNM1 (0.40) TP53ATMCYP2C9ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1239653-C Cyanoacrylate compositions, reaction products, methods of preparation and uses thereof LOCTITE R & D LTD (IE) 2006-02-01 CN claimed
CN-1487983-A Cyanoacrylate compositions curable to flexible polymeric materials ���̩��(R&D)���޹�˾ 2004-04-07 CN claimed
EP-0824316-A4 COMPOSITIONS AND METHODS FOR STIMULATING HAIR GROWTH NIELSEN THOR B (US) 2001-01-17 EP claimed
US-5767152-A USING A CYANOCARBOXYLIC ACID S.N. BIOTECH, INC. 1998-06-16 US claimed
EP-0824316-A1 COMPOSITIONS AND METHODS FOR STIMULATING HAIR GROWTH Nielsen, Thor, B. (US) 1998-02-25 EP claimed
WO-1996034526-A1 COMPOSITIONS AND METHODS FOR STIMULATING HAIR GROWTH NIELSEN THOR B (US) 1996-11-07 WO claimed
CN-112584824-A Nanoparticles 新泰福托特股份有限公司 2021-03-30 CN disclosed
CN-102264852-A Adhesive composition 2011-11-30 CN disclosed
CN-101305064-A Binding agent, sealant and paint containing glass particle as filling material HENKEL AG & CO KGAA (DE) 2008-11-12 CN disclosed
CN-101305040-A Binding agent, sealant and paint containing glass particle as filling material HENKEL AG & CO KGAA (DE) 2008-11-12 CN disclosed
CN-1239653-C Cyanoacrylate compositions, reaction products, methods of preparation and uses thereof LOCTITE R & D LTD (IE) 2006-02-01 CN disclosed
CN-1487983-A Cyanoacrylate compositions curable to flexible polymeric materials ���̩��(R&D)���޹�˾ 2004-04-07 CN disclosed