Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7745813 | 0.88 | ALDH1A1 (0.54) | TSHRMAPK1ALDH1A1NPSR1 | |
| SCHEMBL7740569 | 0.81 | TSHR (0.53) | TSHRMAPK1TP53POLB | |
| SCHEMBL16163238 | 0.78 | TSHR (0.53) | TSHRMAPK1 | |
| SCHEMBL16163229 | 0.76 | TSHR (0.51) | TSHRMAPK1 | |
| SCHEMBL16163321 | 0.76 | TSHR (0.51) | TSHRMAPK1 | |
| SCHEMBL22521641 | 0.74 | CNR2 (0.43) | — | |
| SCHEMBL14941421 | 0.70 | TSHR (0.51) | TSHRMAPK1TP53POLB | |
| SCHEMBL16163364 | 0.70 | TSHR (0.51) | TSHRMAPK1TP53POLB | |
| SCHEMBL2879767 | 0.70 | TSHR (0.48) | TSHRMAPK1TP53POLB | |
| SCHEMBL7741104 | 0.70 | TSHR (0.55) | TSHRMAPK1ALDH1A1NPSR1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |