Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | TP53 | P04637 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 4/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.30 |
| ▸ | NOS1 | P29475 | 1/20 | 0.30 |
| ▸ | NOS2 | P35228 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7741750 | 0.85 | CYP3A4 (0.44) | CYP3A4TSHRPTK2BMEN1KMT2A | |
| SCHEMBL7745821 | 0.82 | CYP3A4 (0.48) | CYP3A4TSHRMEN1KMT2ARAB9A | |
| SCHEMBL8363984 | 0.81 | CYP3A4 (0.39) | CYP3A4TSHRPTK2BMEN1KMT2A | |
| SCHEMBL7741398 | 0.79 | CYP3A4 (0.50) | CYP3A4TSHRPTK2BMEN1KMT2A | |
| SCHEMBL7746706 | 0.79 | CYP3A4 (0.40) | CYP3A4TSHRMEN1KMT2ARAB9A | |
| SCHEMBL7741391 | 0.78 | CYP3A4 (0.37) | CYP3A4 | |
| SCHEMBL8363985 | 0.76 | CYP3A4 (0.40) | CYP3A4MEN1KMT2ARAB9ATP53 | |
| SCHEMBL7746104 | 0.74 | TSHR (0.35) | TSHRPTK2BMEN1KMT2ARAB9A | |
| SCHEMBL7741649 | 0.73 | RAB9A (0.40) | TSHRPTK2BMEN1KMT2ARAB9A | |
| SCHEMBL7746259 | 0.73 | CYP3A4 (0.35) | CYP3A4TSHRPTK2BMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |