Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.65 |
| ▸ | CMA1 | P23946 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 2/20 | 0.49 |
| ▸ | AGXT | P21549 | 2/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28386117 | 0.82 | TAAR1 (0.68) | TAAR1CMA1IDO1AGXTCHRM2 | |
| SCHEMBL449889 | 0.80 | TAAR1 (0.76) | TAAR1CMA1IDO1AGXTCHRM2 | |
| SCHEMBL3742486 | 0.79 | SLC6A4 (0.58) | CMA1IDO1AGXTCYP1A2 | |
| (S)-M-Methoxyamphetamine SCHEMBL30813013 | 0.79 | TAAR1 (1.00) | TAAR1IDO1AGXTSIGMAR1 | |
| (S)-M-Methoxyamphetamine SCHEMBL11461072 | 0.79 | TAAR1 (1.00) | TAAR1IDO1AGXTSIGMAR1 | |
| (S)-M-Methoxyamphetamine SCHEMBL3293027 | 0.79 | TAAR1 (1.00) | TAAR1IDO1AGXTSIGMAR1 | |
| (S)-M-Methoxyamphetamine SCHEMBL269071 | 0.79 | TAAR1 (1.00) | TAAR1IDO1AGXTSIGMAR1 | |
| SCHEMBL3163360 | 0.77 | TAAR1 (0.71) | TAAR1CMA1IDO1AGXTCHRM2 | |
| SCHEMBL29365903 | 0.77 | TAAR1 (0.71) | TAAR1CMA1IDO1AGXTCHRM2 | |
| SCHEMBL9071087 | 0.77 | TAAR1 (0.71) | TAAR1CMA1IDO1AGXTCHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6180792-B1 | DRUGS, ANTISECRETORY AGENTS AND HORMONE INHIBITORS FOR LH-RH | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-01-30 | — | — | US | disclosed |