Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.74 |
| ▸ | MEN1 | O00255 | 3/20 | 0.74 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PPIA | P62937 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | JAK1 | P23458 | 1/20 | 0.41 |
| ▸ | TYK2 | P29597 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10921521 | 0.95 | KMT2A (0.67) | KMT2AMEN1USP2MAPTALOX15 | |
| SCHEMBL10922399 | 0.87 | MEN1 (0.56) | KMT2AMEN1USP2MAPTALOX15 | |
| SCHEMBL8660968 | 0.86 | MEN1 (0.56) | KMT2AMEN1USP2MAPTALOX15 | |
| SCHEMBL10848987 | 0.86 | KMT2A (0.73) | KMT2AMEN1USP2MAPTALOX15 | |
| SCHEMBL10918824 | 0.86 | KMT2A (0.73) | KMT2AMEN1USP2MAPTALOX15 | |
| SCHEMBL10920941 | 0.85 | KMT2A (0.54) | KMT2AMEN1USP2MAPTALOX15 | |
| Teflubenzuron SCHEMBL4217571 | 0.85 | KMT2A (1.00) | KMT2AMEN1USP2MAPTALOX15 | |
| Teflubenzuron SCHEMBL26635 | 0.85 | KMT2A (1.00) | KMT2AMEN1USP2MAPTALOX15 | |
| Teflubenzuron SCHEMBL29352804 | 0.85 | KMT2A (1.00) | KMT2AMEN1USP2MAPTALOX15 | |
| SCHEMBL10390653 | 0.83 | KMT2A (0.82) | KMT2AMEN1USP2MAPTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4622340-A | HALOGENATED PHENYL HALOGENATED BENZOYL UREA, INSECTICIDES, FUNGICIDES | CELAMERCK GMBH & CO., KG (DE) | 1986-11-11 | — | — | US | claimed |
| US-6201012-B1 | MIXTURE OF N-PHENYL-N'-BENZOYL UREA DERIVATIVE AND AN ANTIBIOTIC; ANIMAL PARASITICIDES | NOVARTIS ANIMAL HEALTH US, INC. | 2001-03-13 | — | — | US | disclosed |
| US-5776981-A | Use of acyl urea compounds for controlling endoparasites and ectoparasites of warm-blooded animals | NOVARTIS CORPORATION (US) | 1998-07-07 | — | — | US | disclosed |
| US-5776982-A | Use of acyl urea compounds for controlling endoparasites and ectoparasites of warm-blooded animals | NOVARTIS CORPORATION (US) | 1998-07-07 | — | — | US | disclosed |
| US-5420163-A | Insecticides or miticides | CIBA-GEIGY (US) | 1995-05-30 | — | — | US | disclosed |
| US-5135953-A | Oral or injections; cattle, swine, poultry | CIBA-GEIGY (US) | 1992-08-04 | — | — | US | disclosed |
| US-4918227-A | Process for the preparation of benzoyl ureas | SHELL INTERNATIONALE RESEARCH NAATSCHAPPY B.V. (NL) | 1990-04-17 | — | — | US | disclosed |
| EP-0211004-A1 | USE OF ACYL UREA COMPOUNDS FOR CONTROLLING ENDOPARASITES AND ECTOPARASITES OF WARM-BLOODED ANIMALS | RHONE-POULENC NEDERLAND B.V. (NL) | 1987-02-25 | — | — | EP | disclosed |
| US-4622340-A | HALOGENATED PHENYL HALOGENATED BENZOYL UREA, INSECTICIDES, FUNGICIDES | CELAMERCK GMBH & CO., KG (DE) | 1986-11-11 | — | — | US | disclosed |
| WO-1986003941-A1 | USE OF ACYL UREA COMPOUNDS FOR CONTROLLING ENDOPARASITES AND ECTOPARASITES OF WARM-BLOODED ANIMALS | UNION CARBIDE CORPORATION (US) | 1986-07-17 | — | — | WO | disclosed |
| US-4457943-A | INSECTICIDES, MITICIDES | CELAMERCK GMBH & CO. KG (DE) | 1984-07-03 | — | — | US | disclosed |