Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10922230 | 0.95 | KMT2A (0.51) | MEN1KMT2AALDH1A1NPC1GAA | |
| SCHEMBL10919509 | 0.88 | KMT2A (0.47) | MEN1KMT2AALDH1A1MAPTPOLB | |
| SCHEMBL7746023 | 0.86 | KMT2A (0.74) | MEN1KMT2AMAPTUSP2ALOX15 | |
| SCHEMBL10924181 | 0.86 | ALDH1A1 (0.60) | MEN1KMT2AALDH1A1MAPTPOLB | |
| SCHEMBL10921521 | 0.82 | KMT2A (0.67) | MEN1KMT2AMAPTUSP2ALOX15 | |
| SCHEMBL10777496 | 0.79 | KMT2A (0.46) | MEN1KMT2AALDH1A1MAPTUSP2 | |
| SCHEMBL8656606 | 0.79 | MEN1 (0.43) | MEN1KMT2AALDH1A1MAPTUSP2 | |
| SCHEMBL10920377 | 0.78 | ALDH1A1 (0.67) | MEN1KMT2AALDH1A1MAPTPOLB | |
| SCHEMBL11036349 | 0.77 | GAA (0.53) | MEN1KMT2AALDH1A1EPHX1HPGD | |
| SCHEMBL10817839 | 0.76 | ALDH1A1 (0.59) | MEN1KMT2AALDH1A1HPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776981-A | Use of acyl urea compounds for controlling endoparasites and ectoparasites of warm-blooded animals | NOVARTIS CORPORATION (US) | 1998-07-07 | — | — | US | disclosed |
| US-5776982-A | Use of acyl urea compounds for controlling endoparasites and ectoparasites of warm-blooded animals | NOVARTIS CORPORATION (US) | 1998-07-07 | — | — | US | disclosed |
| US-5420163-A | Insecticides or miticides | CIBA-GEIGY (US) | 1995-05-30 | — | — | US | disclosed |
| US-5135953-A | Oral or injections; cattle, swine, poultry | CIBA-GEIGY (US) | 1992-08-04 | — | — | US | disclosed |
| EP-0211004-A1 | USE OF ACYL UREA COMPOUNDS FOR CONTROLLING ENDOPARASITES AND ECTOPARASITES OF WARM-BLOODED ANIMALS | RHONE-POULENC NEDERLAND B.V. (NL) | 1987-02-25 | — | — | EP | disclosed |
| US-4622340-A | HALOGENATED PHENYL HALOGENATED BENZOYL UREA, INSECTICIDES, FUNGICIDES | CELAMERCK GMBH & CO., KG (DE) | 1986-11-11 | — | — | US | disclosed |
| WO-1986003941-A1 | USE OF ACYL UREA COMPOUNDS FOR CONTROLLING ENDOPARASITES AND ECTOPARASITES OF WARM-BLOODED ANIMALS | UNION CARBIDE CORPORATION (US) | 1986-07-17 | — | — | WO | disclosed |
| US-4457943-A | INSECTICIDES, MITICIDES | CELAMERCK GMBH & CO. KG (DE) | 1984-07-03 | — | — | US | disclosed |