Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.64 |
| ▸ | RAB9A | P51151 | 3/20 | 0.64 |
| ▸ | TP53 | P04637 | 2/20 | 0.64 |
| ▸ | NPC1 | O15118 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 3/20 | 0.64 |
| ▸ | LMNA | P02545 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | TNF | P01375 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7741401 | 0.85 | MEN1 (0.59) | SMN1; SMN2RAB9ATP53NPC1POLB | |
| SCHEMBL1520593 | 0.85 | SMN1; SMN2 (0.64) | SMN1; SMN2RAB9ATP53NPC1POLB | |
| SCHEMBL1520195 | 0.82 | POLB (0.73) | SMN1; SMN2RAB9ATP53NPC1POLB | |
| SCHEMBL4765452 | 0.82 | POLB (0.64) | SMN1; SMN2RAB9ATP53NPC1POLB | |
| SCHEMBL15908544 | 0.81 | SMN1; SMN2 (0.45) | SMN1; SMN2RAB9ATP53NPC1POLB | |
| SCHEMBL9979854 | 0.80 | BACE1 (0.54) | SMN1; SMN2RAB9ATP53NPC1POLB | |
| SCHEMBL1520364 | 0.80 | POLB (0.69) | SMN1; SMN2RAB9ATP53NPC1POLB | |
| SCHEMBL9977940 | 0.79 | SMN1; SMN2 (0.45) | SMN1; SMN2RAB9ATP53NPC1POLB | |
| SCHEMBL6488431 | 0.79 | SMN1; SMN2 (0.61) | SMN1; SMN2RAB9ATP53NPC1POLB | |
| SCHEMBL7740446 | 0.79 | SMN1; SMN2 (0.61) | SMN1; SMN2RAB9ATP53NPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |