Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7746045 | 0.85 | SMN1; SMN2 (0.64) | MEN1KMT2ACXCR4TP53SMN1; SMN2 | |
| SCHEMBL30184968 | 0.84 | TLR8 (0.65) | MEN1KMT2ATP53SMN1; SMN2MAPT | |
| SCHEMBL23100601 | 0.81 | SMN1; SMN2 (0.43) | MEN1KMT2ATP53SMN1; SMN2MAPT | |
| SCHEMBL15908540 | 0.81 | AGTR1 (0.41) | MEN1KMT2A | |
| SCHEMBL9979855 | 0.81 | BACE1 (0.49) | MEN1KMT2ATP53SMN1; SMN2MAPT | |
| Hydrochloric Acid SCHEMBL15301119 | 0.80 | BACE1 (0.48) | MEN1KMT2ATP53SMN1; SMN2MAPT | |
| SCHEMBL3059715 | 0.80 | MEN1 (0.64) | MEN1KMT2ATP53SMN1; SMN2MAPT | |
| SCHEMBL7230292 | 0.79 | LMNA (0.57) | MEN1KMT2ACXCR4TP53SMN1; SMN2 | |
| SCHEMBL102779 | 0.78 | MEN1 (0.77) | MEN1KMT2AMAPTGAAPOLB | |
| SCHEMBL7740722 | 0.77 | MEN1 (0.54) | MEN1KMT2ACXCR4TP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |