SCHEMBL7746098

SCHEMBL7746098

CCCCc1c(C)c(C)c2c(C)cc3cccc4ccc1c2c43

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.41
CYP3A4 P08684 3/20 0.41
HSD17B10 Q99714 3/20 0.41
ALDH1A1 P00352 2/20 0.41
HPGD P15428 2/20 0.41
TDP1 Q9NUW8 2/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
CYP1A2 P05177 5/20 0.36
ERBB2 P04626 1/20 0.36
FYN P06241 1/20 0.36
MAOA P21397 1/20 0.36
ACHE P22303 1/20 0.36
AHR P35869 1/20 0.36
NCEH1 Q6PIU2 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
KDM4E B2RXH2 2/20 0.32
CYP1A1 P04798 2/20 0.31
CYP1B1 Q16678 2/20 0.31
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11131281 0.78 HSD17B10 (0.47) TSHRCYP3A4HSD17B10ALDH1A1HPGD
SCHEMBL27533493 0.78 ALDH1A1 (0.52) TSHRCYP3A4HSD17B10ALDH1A1HPGD
SCHEMBL31414281 0.78 ALDH1A1 (0.52) TSHRCYP3A4HSD17B10ALDH1A1HPGD
SCHEMBL11692367 0.78 HPGD (0.44) TSHRCYP3A4HSD17B10ALDH1A1HPGD
SCHEMBL28537550 0.77 ALDH1A1 (0.50) TSHRCYP3A4HSD17B10ALDH1A1HPGD
SCHEMBL660380 0.77 ALDH1A1 (0.43) TSHRCYP3A4HSD17B10ALDH1A1HPGD
SCHEMBL29227265 0.77 HPGD (0.45) TSHRCYP3A4HSD17B10ALDH1A1HPGD
SCHEMBL11016280 0.74 HPGD (0.47) TSHRCYP3A4HSD17B10ALDH1A1HPGD
SCHEMBL1024836 0.74 CYP3A4 (0.43) TSHRCYP3A4HSD17B10ALDH1A1HPGD
SCHEMBL27909339 0.74 CYP3A4 (0.43) TSHRCYP3A4HSD17B10ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001016328-A2 METHOD FOR THE PRODUCTION OF REGULAR NANOSTRUCTURES NIEDERWEIS MICHAEL (DE) 2001-03-08 WO disclosed