SCHEMBL774629

SCHEMBL774629

C=CCc1ccccc1Oc1ccc(Oc2cccc(CC=C)c2Oc2ccc(Oc3ccc(Oc4ccccc4)cc3)cc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HRH1 P35367 1/20 0.44
SLC6A4 P31645 6/20 0.43
SLC6A2 P23975 4/20 0.43
RIPK1 Q13546 1/20 0.43
ALDH1A1 P00352 3/20 0.38
KDM4E B2RXH2 2/20 0.38
SLC6A3 Q01959 3/20 0.37
HTR2A P28223 3/20 0.37
CYP19A1 P11511 1/20 0.37
FFAR1 O14842 1/20 0.36
HTR1A P08908 1/20 0.36
ADRA2A P08913 1/20 0.36
ADRA2B P18089 1/20 0.36
ADRA2C P18825 1/20 0.36
NISCH Q9Y2I1 1/20 0.36
HPGD P15428 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30083973 0.87 HRH1 (0.55) HRH1SLC6A4SLC6A2RIPK1ALDH1A1
SCHEMBL29106729 0.87 HRH1 (0.46) HRH1SLC6A4SLC6A2RIPK1ALDH1A1
SCHEMBL45176 0.87 HRH1 (0.55) HRH1SLC6A4SLC6A2RIPK1ALDH1A1
SCHEMBL5369650 0.86 HRH1 (0.53) HRH1SLC6A4SLC6A2RIPK1ALDH1A1
SCHEMBL9352980 0.86 HRH1 (0.47) HRH1SLC6A4SLC6A2RIPK1ALDH1A1
Nitrogen SCHEMBL10825524 0.84 HRH1 (0.51) HRH1SLC6A4SLC6A2RIPK1ALDH1A1
SCHEMBL8981215 0.81 SLC6A2 (0.45) HRH1SLC6A4SLC6A2RIPK1ALDH1A1
SCHEMBL28428399 0.81 ALDH1A1 (0.43) HRH1SLC6A4SLC6A2RIPK1ALDH1A1
SCHEMBL278393 0.80 HRH1 (0.46) HRH1SLC6A4SLC6A2RIPK1ALDH1A1
Sulfuric Acid SCHEMBL5907714 0.79 HRH1 (0.46) HRH1SLC6A4SLC6A2RIPK1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9700851-B2 Phenol crosslink for sensor membrane WAVEFORM TECHNOLOGIES, INC. (US) 2017-07-11 US disclosed
US-9700851-B2 Phenol crosslink for sensor membrane WAVEFORM TECHNOLOGIES, INC. (US) 2017-07-11 US disclosed
US-20120067734-A1 PHENOL CROSSLINK FOR SENSOR MEMBRANE BAYER HEALTHCARE LLC (US) 2012-03-22 US disclosed
US-20120067734-A1 PHENOL CROSSLINK FOR SENSOR MEMBRANE BAYER HEALTHCARE LLC (US) 2012-03-22 US disclosed
WO-2011143627-A2 PHENOL CROSSLINK FOR SENSOR MEMBRANE BAYER HEALTHCARE LLC (US) 2011-11-17 WO disclosed