Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6257573 | 0.90 | TSHR (0.38) | TSHRMAPK1ALDH1A1TDP1 | |
| SCHEMBL6246742 | 0.82 | ALDH1A1 (0.44) | SMN1; SMN2LMNAMAPK1ALDH1A1TDP1 | |
| SCHEMBL6243389 | 0.82 | GNRHR (0.41) | MEN1KMT2ASMN1; SMN2LMNATSHR | |
| SCHEMBL7741901 | 0.79 | POLB (0.44) | MEN1KMT2ASMN1; SMN2GAATP53 | |
| SCHEMBL6242389 | 0.75 | GNRHR (0.39) | MEN1KMT2ASMN1; SMN2LMNATSHR | |
| SCHEMBL7746367 | 0.75 | ALDH1A1 (0.48) | MEN1KMT2ASMN1; SMN2LMNAMAPK1 | |
| SCHEMBL7746499 | 0.74 | MEN1 (0.42) | MEN1KMT2ASMN1; SMN2GAATP53 | |
| SCHEMBL7746911 | 0.74 | MEN1 (0.45) | MEN1KMT2ASMN1; SMN2GAATP53 | |
| SCHEMBL7745921 | 0.73 | MEN1 (0.41) | MEN1KMT2ASMN1; SMN2TP53LMNA | |
| SCHEMBL6480122 | 0.73 | TSHR (0.41) | MEN1KMT2AGAATP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |