Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 1/20 | 0.37 |
| ▸ | WNT3A | P56704 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 2/20 | 0.35 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | CASP6 | P55212 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.33 |
| ▸ | IDUA | P35475 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Anthracene SCHEMBL4516327 | 0.82 | POLB (0.43) | POLBCASP6IDUAMEN1KMT2A | |
| Anthracene SCHEMBL4530438 | 0.82 | POLB (0.43) | POLBCASP6IDUAMEN1KMT2A | |
| Dextrose SCHEMBL27294060 | 0.78 | SLC5A2 (0.48) | SLC6A3SLC5A2 | |
| Pyrene SCHEMBL4521971 | 0.77 | KMT2A (0.41) | CES1POLBIDUAMEN1KMT2A | |
| Glucuronate SCHEMBL19410655 | 0.75 | CES1 (0.44) | CES1CYP2C8POLBIDUAMEN1 | |
| Benzothiophene SCHEMBL31094005 | 0.74 | CTNNB1 (0.49) | CTNNB1WNT3AMEN1KMT2AALDH1A1 | |
| Glucuronate SCHEMBL25253417 | 0.74 | IDUA (0.50) | IDUAALDH1A1HPGDKDM4EGLA | |
| Glucuronate SCHEMBL21792734 | 0.74 | IDUA (0.50) | IDUAALDH1A1HPGDKDM4EGLA | |
| Glucuronate SCHEMBL18913128 | 0.74 | IDUA (0.50) | IDUAALDH1A1HPGDKDM4EGLA | |
| Glucuronate SCHEMBL22749019 | 0.74 | IDUA (0.50) | IDUAALDH1A1HPGDKDM4EGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001027129-A1 | GLYCOSIDES AND ORTHOESTER GLYCOSIDES OF RALOXIFENE AND ANALOGUES AND THE USE THEREOF | STRAKAN LIMITED (BM) | 2001-04-19 | — | — | WO | disclosed |
| EP-0735141-A3 | Process for preparation of benzo(b)thiophene glucuronides | ELI LILLY AND COMPANY (US) | 1998-03-04 | — | — | EP | disclosed |
| US-5563054-A | CULTURING STREPTOMYCES IN NUTRIENT MEDIUM | ELI LILLY AND COMPANY (US) | 1996-10-08 | — | — | US | disclosed |
| US-5563054-A | CULTURING STREPTOMYCES IN NUTRIENT MEDIUM | ELI LILLY AND COMPANY (US) | 1996-10-08 | — | — | US | disclosed |
| EP-0735141-A2 | Process for preparation of benzo(b)thiophene glucuronides | ELI LILLY AND COMPANY (US) | 1996-10-02 | — | — | EP | disclosed |
| EP-0735141-A2 | Process for preparation of benzo(b)thiophene glucuronides | ELI LILLY AND COMPANY (US) | 1996-10-02 | — | — | EP | disclosed |