Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.43 |
| ▸ | IDUA | P35475 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | GABRP | O00591 | 1/20 | 0.36 |
| ▸ | GABRD | O14764 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | GAPDH | P04406 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Anthracene SCHEMBL4516327 | 1.00 | POLB (0.43) | POLBCASP6IDUAALDH1A1HPGD | |
| Pyrene SCHEMBL4521971 | 0.85 | KMT2A (0.41) | POLBIDUAALDH1A1HPGDKDM4E | |
| Glucuronate SCHEMBL19410655 | 0.83 | CES1 (0.44) | POLBIDUAALDH1A1HPGDCYP1A2 | |
| Glucuronate SCHEMBL7746376 | 0.82 | CTNNB1 (0.37) | POLBCASP6IDUAALDH1A1HPGD | |
| Glucuronate SCHEMBL8935076 | 0.82 | CYP1A2 (0.49) | POLBALDH1A1HPGDKDM4EGLA | |
| Benzo[Def]Chrysene SCHEMBL4955962 | 0.81 | CYP1A2 (0.54) | POLBALDH1A1HPGDKDM4EGLA | |
| Glucuronate SCHEMBL25253417 | 0.81 | IDUA (0.50) | IDUAALDH1A1HPGDKDM4EGLA | |
| Glucuronate SCHEMBL22749019 | 0.81 | IDUA (0.50) | IDUAALDH1A1HPGDKDM4EGLA | |
| Glucuronate SCHEMBL20094857 | 0.81 | IDUA (0.50) | IDUAALDH1A1HPGDKDM4EGLA | |
| Glucuronate SCHEMBL21312643 | 0.81 | IDUA (0.50) | IDUAALDH1A1HPGDKDM4EGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140295403-A1 | DETECTION OF BIOLOGICAL MOLECULES BY DIFFERENTIAL PARTITIONING OF ENZYME SUBSTRATES AND PRODUCTS | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2014-10-02 | — | — | US | disclosed |
| US-8632966-B2 | Detection of biological molecules by differential partitioning of enzyme substrates and products | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2014-01-21 | — | — | US | disclosed |
| US-20130217041-A1 | DETECTION OF BIOLOGICAL MOLECULES BY DIFFERENTIAL PARTITIONING OF ENZYME SUBSTRATES AND PRODUCTS | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2013-08-22 | — | — | US | disclosed |
| US-8377686-B2 | Detection of biological molecules by differential partitioning of enzyme substrates and products | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2013-02-19 | — | — | US | disclosed |
| US-20090117600-A1 | Detection of biological molecules by differential partitioning of enzyme substrates and products | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2009-05-07 | — | — | US | disclosed |
| US-7402426-B2 | Analyzing microorganism associated with an enzyme in a sample water, food, soil, or a biological sample, enzyme-linked immunosorbent assay, automatic detect fluorescence with optical fiber, separate with polydimethylsiloxane films; diagnostic kits | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2008-07-22 | — | — | US | disclosed |
| EP-1539986-B1 | DETECTION OF BIOLOGICAL MOLECULES BY DIFFERENTIAL PARTITIONING OF ENZYME SUBSTRATES AND PRODUCTS | UNIV KINGSTON (CA) | 2007-07-18 | — | — | EP | disclosed |
| EP-1539986-A1 | DETECTION OF BIOLOGICAL MOLECULES BY DIFFERENTIAL PARTITIONING OF ENZYME SUBSTRATES AND PRODUCTS | Queen's University at Kingston (CA) | 2005-06-15 | — | — | EP | disclosed |
| US-20040106164-A1 | Analyzing microorganism associated with an enzyme in a sample water, food, soil, or a biological sample, enzyme-linked immunosorbent assay, automatic detect fluorescence with optical fiber, separate with polydimethylsiloxane films; diagnostic kits | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2004-06-03 | — | — | US | disclosed |
| WO-2004027084-A1 | DETECTION OF BIOLOGICAL MOLECULES BY DIFFERENTIAL PARTITIONING OF ENZYME SUBSTRATES AND PRODUCTS | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2004-04-01 | — | — | WO | disclosed |