SCHEMBL7746452

SCHEMBL7746452

O=C(O)C(=O)c1ccc(-c2ccccc2)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.60
MAPT P10636 3/20 0.60
CES2 O00748 4/20 0.59
CES1 P23141 3/20 0.59
CPT1B Q92523 1/20 0.58
RAB9A P51151 3/20 0.56
NPC1 O15118 1/20 0.56
CTDSP1 Q9GZU7 1/20 0.56
ERCC5 P28715 1/20 0.55
FEN1 P39748 1/20 0.55
HAO1 Q9UJM8 1/20 0.55
PTPN1 P18031 2/20 0.54
L3MBTL1 Q9Y468 2/20 0.54
GSK3B P49841 1/20 0.54
LMNA P02545 2/20 0.52
CDC25B P30305 1/20 0.52
ATM Q13315 1/20 0.52
FFAR1 O14842 1/20 0.52
CYP1A2 P05177 1/20 0.52
HIF1A Q16665 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14124772 1.00 SMN1; SMN2 (0.60) SMN1; SMN2MAPTCES2CES1CPT1B
SCHEMBL9647147 0.90 CES2 (0.74) SMN1; SMN2MAPTCES2CES1RAB9A
SCHEMBL14211984 0.87 CES2 (0.79) SMN1; SMN2MAPTCES2CES1RAB9A
SCHEMBL11312963 0.84 CES2 (0.83) SMN1; SMN2MAPTCES2CES1RAB9A
Benzoyl Formic Acid SCHEMBL15180795 0.84 CES2 (0.77) SMN1; SMN2MAPTCES2CES1CPT1B
Benzoyl Formic Acid SCHEMBL15180800 0.84 CES2 (0.77) SMN1; SMN2MAPTCES2CES1CPT1B
Benzoyl Formic Acid SCHEMBL38943 0.84 CES2 (0.77) SMN1; SMN2MAPTCES2CES1CPT1B
Benzoyl Formic Acid SCHEMBL15180886 0.84 CES2 (0.77) SMN1; SMN2MAPTCES2CES1CPT1B
Benzoyl Formic Acid SCHEMBL15180809 0.84 CES2 (0.77) SMN1; SMN2MAPTCES2CES1CPT1B
Benzoyl Formic Acid SCHEMBL15180811 0.84 CES2 (0.77) SMN1; SMN2MAPTCES2CES1CPT1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114436793-A Method for synthesizing mild alpha, alpha' -diaryl ketone 赣南医学院 2022-05-06 CN claimed
CN-114436793-B Mild synthesis method of alpha, alpha' -diaryl ketone 赣南医学院 2023-12-26 CN disclosed
CN-114752955-B Method for electrochemically synthesizing N-nitroso-2-aminobenzophenone compound 广西师范大学 2023-06-16 CN disclosed
CN-114752955-A Method for electrochemically synthesizing N-nitroso-2-aminobenzophenone compound 广西师范大学 2022-07-15 CN disclosed
CN-112135862-B Composition for improving the adhesion of textile materials and related reinforced textile materials 博舍工业公司 2022-06-03 CN disclosed
CN-114436793-A Method for synthesizing mild alpha, alpha' -diaryl ketone 赣南医学院 2022-05-06 CN disclosed
CN-112135862-A Composition for improving the adhesion of textile materials and related reinforced textile materials 博舍工业公司 2020-12-25 CN disclosed
US-7396488-B2 Light emitting device and fluorescent material MITSUBISHI CHEMICAL CORPORATION (JP) 2008-07-08 US disclosed
US-7396488-B2 Light emitting device and fluorescent material MITSUBISHI CHEMICAL CORPORATION (JP) 2008-07-08 US disclosed
US-7282160-B2 Light emitting device and fluorescent material MITSUBISHI CHEMICAL CORPORATION (JP) 2007-10-16 US disclosed
WO-2001010836-A1 METHOD OF TREATING HAIR LOSS USING MULTIVALENT KETOAMIDES AND AMIDES THE PROCTER & GAMBLE COMPANY (US) 2001-02-15 WO disclosed
WO-2001010821-A1 MULTIVALENT EXOCYCLIC DIKETO COMPOUNDS THE PROCTER & GAMBLE COMPANY (US) 2001-02-15 WO disclosed
WO-2001010839-A2 MULTIVALENT SUBSTITUTED KETOAMIDES AND AMIDES FOR TREATING HAIR LOSS THE PROCTER & GAMBLE COMPANY (US) 2001-02-15 WO disclosed
WO-2000053313-A2 LANTHANIDE CATALYSTS FOR SYNTHESIS OF COMPOUNDS AND COMBINATORIAL LIBRARIES ARQULE, INC. (US) 2000-09-14 WO disclosed
EP-0938482-A1 5-SUBSTITUTED AND 5,5-DISUBSTITUTED-3,4-DIHYDROXY-2(5H)-FURANONES AND METHODS OF USE THEREFOR Oxis International, Inc. (US) 1999-09-01 EP disclosed
EP-0900197-A1 BETA-THIOPROPIONYL-AMINOACID DERIVATIVES AND THEIR USE AS BETA-LACTAMASE INHIBITORS SMITHKLINE BEECHAM PLC (GB) 1999-03-10 EP disclosed
WO-1998007714-A1 5-SUBSTITUTED AND 5,5-DISUBSTITUTED-3,4-DIHYDROXY-2(5H)-FURANONES AND METHODS OF USE THEREFOR OXIS INTERNATIONAL, INC. (US) 1998-02-26 WO disclosed
WO-1997030027-A1 BETA-THIOPROPIONYL-AMINOACID DERIVATIVES AND THEIR USE AS BETA-LACTAMASE INHIBITORS SMITHKLINE BEECHAM PLC (GB) 1997-08-21 WO disclosed
US-3969401-A ANTIINFLAMMATORY, ANALGESIC, ANTIPYRETIC WILLIAM H. RORER, INC. (US) 1976-07-13 US disclosed
US-3941821-A ANTIINFLAMMATORY, ANALGESICS, ANTIPYRETICS WILLIAM H. RORER, INC. (US) 1976-03-02 US disclosed