Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 6/20 | 0.56 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.56 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.56 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.44 |
| ▸ | SLC18A2 | Q05940 | 8/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CCR5 | P51681 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7744376 | 1.00 | OPRL1 (0.56) | OPRL1OPRM1OPRK1CHRM2CHRM4 | |
| SCHEMBL6586061 | 0.94 | OPRL1 (0.58) | OPRL1OPRM1OPRK1CHRM2CHRM4 | |
| SCHEMBL4916517 | 0.94 | OPRL1 (0.58) | OPRL1OPRM1OPRK1CHRM2CHRM4 | |
| SCHEMBL8136817 | 0.92 | OPRL1 (0.56) | OPRL1OPRM1OPRK1CHRM2CHRM4 | |
| SCHEMBL8121203 | 0.90 | OPRL1 (0.58) | OPRL1OPRM1OPRK1CHRM2CHRM4 | |
| SCHEMBL4916956 | 0.88 | OPRL1 (0.66) | OPRL1OPRM1OPRK1CHRM2CHRM4 | |
| SCHEMBL4920275 | 0.88 | OPRL1 (0.66) | OPRL1OPRM1OPRK1CHRM2CHRM4 | |
| Lithium Ion SCHEMBL7745039 | 0.86 | OPRL1 (0.64) | OPRL1OPRM1OPRK1CHRM2CHRM4 | |
| SCHEMBL6585954 | 0.83 | OPRL1 (0.51) | OPRL1OPRM1OPRK1CHRM2CHRM4 | |
| SCHEMBL6586613 | 0.83 | OPRM1 (0.43) | OPRL1OPRM1OPRK1SLC18A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6258825-B1 | ANALGESIC, A RELIEVER AGAINST TOLERANCE TO A NARCOTIC ANALGESIC REPRESENTED BY MORPHINE, REMEDY FOR PARKINSONISM, A REMEDY FOR CHOREA, AN ANTIDEPRESSANT, A REMEDY FOR DIABETES INSIPIDUS, A REMEDY FOR POLYURIA, OR HYPOTENSION | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2001-07-10 | — | — | US | disclosed |