Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | GAA | P10253 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 7/20 | 0.45 |
| ▸ | RAB9A | P51151 | 6/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7747084 | 1.00 | MEN1 (0.58) | MEN1KMT2AGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL7747580 | 0.87 | ALDH1A1 (0.74) | MEN1KMT2AGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL7747583 | 0.87 | ALDH1A1 (0.74) | MEN1KMT2AGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL13674722 | 0.85 | MEN1 (0.50) | MEN1KMT2AGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL13674723 | 0.85 | MEN1 (0.56) | MEN1KMT2AGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL13674721 | 0.85 | MEN1 (0.50) | MEN1KMT2AGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL7746961 | 0.83 | ALDH1A1 (0.52) | MEN1KMT2AGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL7746964 | 0.83 | ALDH1A1 (0.52) | MEN1KMT2AGAAALDH1A1SMN1; SMN2 | |
| Acetic Acid SCHEMBL21519394 | 0.82 | ALDH1A1 (0.66) | MEN1KMT2AGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL21538116 | 0.80 | MEN1 (0.47) | MEN1KMT2AGAAALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001025192-A1 | GUANIDINE DERIVATIVES AND THEIR USE IN THE PRODUCTION OF A MEDICAMENT FOR BLOCKING XANTHINE OXIDASE/DEHYDROGENASE | MELACURE THERAPEUTICS AB (SE) | 2001-04-12 | — | — | WO | disclosed |