Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNRHR | P30968 | 20/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7749111 | 0.93 | GNRHR (0.68) | GNRHR | |
| Hydrochloric Acid SCHEMBL7748993 | 0.89 | GNRHR (0.62) | GNRHR | |
| SCHEMBL7202812 | 0.85 | GNRHR (0.90) | GNRHR | |
| SCHEMBL778511 | 0.76 | GNRHR (0.78) | GNRHR | |
| SCHEMBL7591971 | 0.74 | GNRHR (0.54) | GNRHR | |
| SCHEMBL805090 | 0.74 | GNRHR (0.77) | GNRHR | |
| SCHEMBL4058798 | 0.74 | GNRHR (0.72) | GNRHR | |
| SCHEMBL778208 | 0.74 | GNRHR (0.78) | GNRHR | |
| Hydrochloric Acid SCHEMBL778601 | 0.74 | GNRHR (0.76) | GNRHR | |
| Hydrochloric Acid SCHEMBL7203755 | 0.74 | GNRHR (0.85) | GNRHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6187788-B1 | THIENO(2,3-B)(DIHYDRO)PYRIDINE DERIVATIVES; GONADOTROPIN-RELEASING HORMONE ANTAGONISTS; ANTICARCINOGENIC AGENTS; SEXUAL AND UROGENITAL DISORDERS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-02-13 | — | — | US | disclosed |
| US-6180792-B1 | DRUGS, ANTISECRETORY AGENTS AND HORMONE INHIBITORS FOR LH-RH | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-01-30 | — | — | US | disclosed |
| WO-1995028405-A1 | BICYCLIC THIOPHENE DERIVATIVES AND USE AS GONADOTROPIN RELEASING HORMONE ANTAGONISTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-10-26 | — | — | WO | disclosed |