Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 5/20 | 0.46 |
| ▸ | CYP46A1 | Q9Y6A2 | 2/20 | 0.45 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.45 |
| ▸ | CCKBR | P32239 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.45 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4167455 | 0.88 | PDE7A (0.49) | PGRCYP46A1NR3C1NR1I2ADRB1 | |
| SCHEMBL653433 | 0.85 | PGR (0.46) | PGRCYP46A1NR3C1NR1I2ADRB1 | |
| SCHEMBL31122188 | 0.85 | PGR (0.46) | PGRCYP46A1NR3C1NR1I2ADRB1 | |
| Hydrochloric Acid SCHEMBL10917557 | 0.84 | PGR (0.45) | PGRCYP46A1NR3C1NR1I2ADRB1 | |
| SCHEMBL10952538 | 0.82 | AVPR1A (0.47) | PGRCYP46A1NR3C1NR1I2ADRB1 | |
| SCHEMBL17205437 | 0.80 | PGR (0.44) | PGRCYP46A1NR3C1NR1I2ADRB1 | |
| SCHEMBL18797014 | 0.80 | PGR (0.44) | PGRCYP46A1NR3C1NR1I2ADRB1 | |
| Hydrochloric Acid SCHEMBL18797045 | 0.79 | PGR (0.43) | PGRCYP46A1NR3C1NR1I2ADRB1 | |
| Hydrochloric Acid SCHEMBL17205976 | 0.79 | PGR (0.43) | PGRCYP46A1NR3C1NR1I2ADRB1 | |
| SCHEMBL13110266 | 0.78 | MAPK1 (0.47) | MAPTMAPK1PDE7AAVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001022919-A2 | SPIRO[BICYCLIC -AZACYCLOALKYL AND -CYCLOALKYL] DERIVATIVES AND USES THEREOF | MERCK & CO., INC. (US) | 2001-04-05 | — | — | WO | disclosed |