Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.66 |
| ▸ | ALPL | P05186 | 1/20 | 0.66 |
| ▸ | POLB | P06746 | 1/20 | 0.66 |
| ▸ | ALPI | P09923 | 1/20 | 0.66 |
| ▸ | ALPG | P10696 | 1/20 | 0.66 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.66 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | BCHE | P06276 | 1/20 | 0.51 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7747561 | 1.00 | MEN1 (0.66) | MEN1KMT2AL3MBTL1ALPLPOLB | |
| SCHEMBL6743215 | 0.87 | KMT2A (0.51) | MEN1KMT2AL3MBTL1ALPLPOLB | |
| SCHEMBL6743212 | 0.87 | KMT2A (0.51) | MEN1KMT2AL3MBTL1ALPLPOLB | |
| SCHEMBL19449624 | 0.86 | MEN1 (0.70) | MEN1KMT2AL3MBTL1ALPLPOLB | |
| Hydrochloric Acid SCHEMBL17560846 | 0.85 | MEN1 (0.68) | MEN1KMT2AL3MBTL1ALPLPOLB | |
| SCHEMBL31105659 | 0.84 | TTR (0.49) | MEN1KMT2AL3MBTL1ALPLPOLB | |
| SCHEMBL23996048 | 0.83 | MEN1 (0.66) | MEN1KMT2AL3MBTL1ALPLPOLB | |
| SCHEMBL13641767 | 0.83 | L3MBTL1 (0.66) | MEN1KMT2AL3MBTL1ALPLPOLB | |
| SCHEMBL6740122 | 0.83 | ADORA2A (0.57) | MEN1KMT2AL3MBTL1ALPLPOLB | |
| SCHEMBL6740126 | 0.83 | ADORA2A (0.57) | MEN1KMT2AL3MBTL1ALPLPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001025192-A1 | GUANIDINE DERIVATIVES AND THEIR USE IN THE PRODUCTION OF A MEDICAMENT FOR BLOCKING XANTHINE OXIDASE/DEHYDROGENASE | MELACURE THERAPEUTICS AB (SE) | 2001-04-12 | — | — | WO | claimed |