Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 4/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7746326 | 1.00 | MAPK1 (0.56) | MAPK1CYP1A2CYP2C19CYP2C9KDM4E | |
| SCHEMBL7747744 | 1.00 | MAPK1 (0.56) | MAPK1CYP1A2CYP2C19CYP2C9KDM4E | |
| SCHEMBL7746330 | 0.86 | MAPK1 (0.53) | MAPK1CYP1A2CYP2C19CYP2C9KDM4E | |
| SCHEMBL7749505 | 0.86 | MAPK1 (0.53) | MAPK1CYP1A2CYP2C19CYP2C9KDM4E | |
| SCHEMBL14878904 | 0.84 | MAPK1 (0.50) | MAPK1CYP1A2CYP2C19CYP2C9KDM4E | |
| SCHEMBL4572006 | 0.83 | MAPK1 (0.55) | MAPK1CYP1A2CYP2C19CYP2C9KDM4E | |
| SCHEMBL7747327 | 0.83 | MAPK1 (0.55) | MAPK1CYP1A2CYP2C19CYP2C9KDM4E | |
| SCHEMBL17550596 | 0.81 | POLB (0.49) | MAPK1CYP1A2CYP2C19CYP2C9KDM4E | |
| SCHEMBL25990997 | 0.81 | MAPK1 (0.45) | MAPK1CYP1A2CYP2C19CYP2C9KDM4E | |
| SCHEMBL14302990 | 0.81 | MAPK1 (0.52) | MAPK1CYP1A2CYP2C19CYP2C9KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001018231-A2 | METHOD FOR PRODUCING (R) OR (S)-HYDROXY-η-BUTYROLACTONE | LONZA AG (CH) | 2001-03-15 | — | — | WO | disclosed |